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Information about Zona Pellucida

Human ovum. The zona pellucida is seen as a thick clear girdle surrounded by the cells of the corona radiata.
subject #3 38
MeSH Zona+Pellucida
Dorlands/Elsevier z_01/12869767
The zona pellucida (or zona striata in older texts) is a glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it.

This structure binds spermatozoa, and is required to initiate the acrosome reaction.

The zona glycoprotein, ZP3, is responsible for sperm binding, adhering to proteins on the sperm plasma membrane. There is evidence that ZP3 is then involved in the induction of the acrosome reaction, whereby a spermatozoon releases the contents of the acrosomal vesicle.

Function in humans

In humans, five days after the fertilization, the blastocyst performs zona hatching; the zona pellucida degenerates and decomposes to be replaced by the underlying layer of trophoblastic cells.

The zona pellucida is essential for oocyte survival and fertilization.

Immunocontraception

Glycoproteins in ZP1, 2, and 3 are targets for immunocontraception.

In non-mammalian animals, the zona pellucida (called vitelline layer) plays an important role in preventing breeding of different species, especially in species that fertilize outside of the body (e.g. fish).

The zona pellucida is commonly used to control wildlife population problems by immunocontraception. When the zona pellucida of one animal species is injected into the bloodstream of another, it results in sterility of the second species due to immune response. This effect can be temporary or permanent, depending on the method used. In New Jersey, Porcine zona pellucida is used to keep deer populations low, and this process is commonly referred to as "spay-vac".

Additional images


Early folliculogenesis from primordial to early tertiary.

First stages of segmentation of a mammalian ovum.

Section of vesicular ovarian follicle of cat. x50.


References

  • Oehninger S (2003). "Biochemical and functional characterization of the human zona pellucida.". Reprod Biomed Online 7 (6): 641-8. PMID 14748962. 
  • Bagnell, C. 2005. "Animal Reproduction". Rutgers University Department of Animal Sciences.

External links

 •  • [ e]
Female reproductive system
Ovaries/OogenesisGerminal epithelium • Tunica albuginea • cortex (Cumulus oophorus, Stroma) • Medulla
Follicles/Folliculogenesiscorpus (hemorrhagicum, luteum, albicans) • Theca folliculi (externa, interna) • Follicular antrum (Follicular fluid) • Corona radiata • Zona pellucida • Membrana granulosa (Granulosa cells)
LigamentsProper • Suspensory • Round • Broad (Mesovarium, Mesosalpinx, Mesometrium) • Cardinal
Fallopian tubesIsthmus • Ampulla • Infundibulum • Fimbria
Uteruscervix/neck (External orifice, Canal of the cervix, Internal orifice) • corpus/body (Cavity of the body, Fundus) • layers (Endometrium, Myometrium, Perimetrium)
VulvaMons pubis • Labium  (Labial commissures, Frenulum labiorum pudendi, Labia majora, Cleft of venus, Labia minora, Vulval vestibule, interlabial sulci) • Clitoris  (Clitoral hood , Clitoral glans, Frenulum clitoridis, Clitoral crura, Corpus cavernosa, Vestibular bulbs) • Vagina (Bartholin's glands, Bartholin's ducts, Skene's glands, Skene's ducts, Fossa of vestibule of vagina, Vaginal fornix, Hymen)
BreastMammary glands • Nipple • Areola • Lactiferous duct
OtherG-spot • Urethral sponge
ovum (plural ova) is a haploid female reproductive cell or gamete. The word is derived from Latin, meaning egg or egg cell. Both animals and embryophytes have ova. The term ovule
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For the structure in neuroanatomy, see Corona radiata.
The corona radiata surround an ovum or unfertilized egg cell, and consist of two or three strata (layers) of follicular cells.
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Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed
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Elsevier, the world's largest publisher of medical and scientific literature, forms part of the Reed Elsevier group. Based in Amsterdam, the company has substantial operations in the UK, USA and elsewhere.
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Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to their polypeptide backbones. Basically, glycoprotein is a biomolecule composed of a protein and a carbohydrate (an oligosaccharide).
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An oocyte, ovocyte, or rarely oöcyte, is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum. An Oocyte is part the Ovary development, Different names for different stages.
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A spermatozoon or spermatozoan (pl. spermatozoa), from the ancient Greek σπέρμα (seed) and ζῷον (living being) and more commonly known as a sperm cell
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acrosome reaction is the reaction which occurs in the acrosome of the sperm as it approaches the zona pellucida.

As the sperm approaches the egg, the membrane surrounding the acrosome fuses with the plasma membrane of the sperm, exposing the contents of the acrosome and
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ZP3 is the receptor in the zona pellucida which binds with the acrosome of the sperm in the acrosome reaction.

External links

  • MeSH ZP3+protein,+human

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Proteins are large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid residues.
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In spermatozoa of many animals, the Acrosome is an organelle that develops over the anterior half of the spermatozoon's head. It is a cap-like structure derived from the Golgi apparatus. Acrosome formation is completed during testicular maturation.
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Zona hatching is a phenomenon occurring during prenatal development. Prior to this event, the predecessor of the child, in the form of a blastocyst, is surrounded by a glycoprotein sphere called the zona pellucida.
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An oocyte, ovocyte, or rarely oöcyte, is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum. An Oocyte is part the Ovary development, Different names for different stages.
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Fertilization (also known as conception, fecundation and syngamy), is fusion of gametes to form a new organism of the same species. In animals, the process involves a sperm fusing with an ovum, which eventually leads to the development of an embryo.
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The vitelline membrane is a structure directly adjacent to the outer surface of the plasma membrane of an ovum. It is composed mostly of protein fibers, with protein receptors needed for sperm binding, binding to sperm plasma membrane receptors.
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State of New Jersey

Flag of New Jersey Seal
Nickname(s): Garden State[1]
Motto(s): Liberty and prosperity

Official language(s) English de facto

Capital Trenton

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Porcine zona pellucida is a form of zona pellucida extracted from the ovaries of pigs. Often referred to by the initials PZP.

The zona pellucida is a thick membrane that surrounds the unfertilized eggs of mammals.
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Cervidae
Goldfuss, 1820

Subfamilies

Capreolinae/Odocoileinae
Cervinae
Hydropotinae
Muntiacinae

A deer is a ruminant mammal belonging to the family Cervidae.
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ovum (plural ova) is a haploid female reproductive cell or gamete. The word is derived from Latin, meaning egg or egg cell. Both animals and embryophytes have ova. The term ovule
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Boston University (BU) is a private research university located in Boston, Massachusetts, United States. Although chartered by the Massachusetts Legislature in 1869, Boston University traces its roots to the establishment of the Newbury Biblical Institute in Newbury,
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Boston University (BU) is a private research university located in Boston, Massachusetts, United States. Although chartered by the Massachusetts Legislature in 1869, Boston University traces its roots to the establishment of the Newbury Biblical Institute in Newbury,
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Yearbook = El Rodeo
Nickname Trojans
Men/Women of Troy
Mascot Traveler
Fight song Fight On
Athletics 19 varsity teams,
NCAA Division I
Affiliations AAU
Pac-10
Nobel laureates 1
Website www.usc.edu , www.usctrojans.
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Yearbook = El Rodeo
Nickname Trojans
Men/Women of Troy
Mascot Traveler
Fight song Fight On
Athletics 19 varsity teams,
NCAA Division I
Affiliations AAU
Pac-10
Nobel laureates 1
Website www.usc.edu , www.usctrojans.
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University of California, Davis, commonly known as UC Davis, is one of the ten campuses of the University of California, and was established as the University Farm in 1905.
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Sexual reproduction.


The human female reproductive system contains two main parts: the vagina and uterus, which act as the receptacle for the male's sperm, and the ovaries, which produce the female's ova.
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The reproductive system is the ensembles and interactions of organs and/or substances within an organism that strictly pertain to reproduction. As an example, this would include in the case of female mammals, the hormone estrogen, ova, and the uterus and the vagina, and the breasts.
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For ovary as part of plants see ovary (plants)
An ovary is an egg-producing reproductive organ found in female organisms. They are usually purple. It is often found in pairs as part of the vertebrate female reproductive system.
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Oogenesis or rarely oögenesis is the creation of an ovum (egg cell). It is the female process of gametogenesis. It involves the various stages of immature ova.

Oogenesis in mammals

In mammals, oogenesis occurs in the ovarian follicle of the ovary.
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