Information about Zona Hatching
Zona hatching is a phenomenon occurring during prenatal development. Prior to this event, the predecessor of the child, in the form of a blastocyst, is surrounded by a glycoprotein sphere called the zona pellucida. To be able to perform implantation on the uterine wall, the blastocyst first needs to get rid of the zona pellucida[1]. This lysis of the zona pellucida is called the zona hatching.
Uses of the term
In some situations, the term "hatching" is used only for artificial ways to free the blastocyst from the zona pellucida, and not the natural lysis of it. An example of such artificial way is Assisted zona hatching.References
Prenatal development is the process in which an embryo or fetus (or foetus) gestates during pregnancy, from fertilization until birth. Often, the terms fetal development, foetal development, or embryology are used in a similar sense.
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The blastocyst is an early stage of the human (or other mammal) development early in pregnancy. It is the structure formed in early human embryogenesis, after the formation of the blastocele, but before implantation.
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The zona pellucida (or zona striata in older texts) is a glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it.
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Implantation is an event that occurs early in pregnancy in which the embryo adheres to the wall of uterus. At this stage of prenatal development, the embryo is a blastocyst. It is by this adhesion the fetus receives the oxygen and the nutrients from the mother to be able to grow.
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The word uterine can refer to different meanings:
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- relating to or near the uterus or womb
- having the same mother, but different fathers, see matrilineality
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Assisted zona hatching (AZH) is a procedure of Assisted reproductive technology, increasing the chances of pregnancy[1].
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Indication
Normally, the blastocyst performs zona hatching, getting rid of the surrounding zona pellucida, to be able to implant in the..... Click the link for more information.
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