Yaws

Information about Yaws

*Classification & external resources*

Nodules on the elbow resulting from a Treponema pertenue bacterial infection.
ICD-10	A66.
ICD-9	102

Yaws (also Pétasse tropica, thymosis, polypapilloma tropicum or pian) is a tropical infection of the skin, bones and joints caused by the spirochete bacterium Treponema pertenue. Other treponematosis diseases are bejel (Treponema endemicum), pinta (Treponema carateum), syphilis (Treponema pallidum), and Lyme Disease (Borrelia burgdorferi)

Epidemiology

The disease is transmitted by skin contact with infected individuals or eye gnats, the spirochete entering through an existing cut or similar damage. Within ninety days (but usually less than a month) of infection a painless but distinctive 'mother yaw' ulcer appears. These tracts heal with keloid formation which can cause deformities, disabilities and limb contractures. The bone lesions caused are periostitis, osteitis, and osteomyelitis, damage to the tibia can lead to a condition known as sabre shins. In a very few cases a condition known as goundou is caused where growths on the nasal maxillae can result in extensive and severe damage to the nose and palate.

The largest group afflicted by yaws are children aged 6 to 10 years in tropical areas of the Americas, Africa, Asia or Oceania. There were World Health Organization funded campaigns against yaws from 1954 to 1963 which greatly reduced the incidence of the disease, although more recently numbers have risen again.

The disease is identified from blood tests or by a lesion sample through a darkfield examination under a microscope. Treatment is by a single dose of penicillin, erythromycin or tetracycline, recurrence or relapse is uncommon.

Examination of ancient remains has led to the suggestion that yaws has affected hominids for the last 1.5 million years. The current name is believed to be of Carib origin, "yaya" meaning sore; frambesia is a Modern Latin word inspired by the French word Pétasse ("raspberry").

Occurrence

Yaws was nearly eradicated by a worldwide treatment program in the 1950s, which reduced the number of sufferers of yaws from an estimated 50 million to nearly zero. However, the World Health Organization reported in January 2007 that yaws is on the rise again, with roughly a half a million sufferers, mostly in poor, rural areas.^[1]

References

1. ^ WHO: Flesh-Eating Disease Making Comeback. Associated Press (January 25, 2007). Retrieved on 2007-01-25.

McNeill, Katie H. "Plagues and People." Bantam Doubleday Dell Publishing Group, Inc., New York, NY, 1976, ISBN 0-385-12122-9.

• • [ e] Bacterial diseases (primarily , )
G+/Firmicutes	Clostridium (Pseudomembranous colitis, Botulism, Tetanus, Gas gangrene) - Streptococcus A and B (Scarlet fever, Erysipelas) - Staphylococcus (Toxic shock syndrome) - Bacilli (Anthrax, Listeriosis)
G+/Actinobacteria	Mycobacterium: Tuberculosis (Ghon focus, Ghon's complex, Tuberculous meningitis, Pott's disease, Scrofula, Bazin disease, Lupus vulgaris, Miliary tuberculosis) - Leprosy - Lady Windermere syndrome - Buruli ulcer - Actinomycetales: Actinomycosis - Nocardiosis - Diphtheria - Erythrasma
G-/Spirochetal	Syphilis (Bejel) - Yaws - Pinta - Relapsing fever - Noma - Trench mouth - Lyme disease - Rat-bite fever (Sodoku) - Leptospirosis
G-/Chlamydiae	Chlamydia - Lymphogranuloma venereum - Psittacosis - Trachoma
G-/α Proteobacteria	Rickettsioses (Typhus, Scrub typhus, Rocky Mountain spotted fever, Boutonneuse fever, Q fever, Trench fever, Rickettsialpox) - Brucellosis - Cat scratch fever - Bartonellosis (Bacillary angiomatosis)
G-/β&γ Proteobacteria	Salmonella (Typhoid fever, Paratyphoid fever, Salmonellosis) - other intestinal (Cholera, Shigellosis) - Zoonotic (Bubonic plague, Tularemia, Glanders, Melioidosis, Pasteurellosis) - Other: Pertussis - Meningococcus (Meningococcemia, Waterhouse-Friderichsen syndrome) - Legionellosis - Brazilian purpuric fever - Chancroid - Donovanosis - Gonorrhea

For other uses of "ICD", see ICD (disambiguation).

The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD
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List of ICD-10 codes. The version for 2007 is available online at [1]

Chapter Blocks Title
I Certain infectious and parasitic diseases
II Neoplasms
III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
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For other uses of "ICD", see ICD (disambiguation).

The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD
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The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. These codes are in the public domain.

In humans

The tibia or shin bone, in human anatomy, is found medial (towards the middle) and anterior (towards the front) to the other such bone, the fibula.
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child (plural: children) is primarily a boy or girl who has not reached puberty.^[1]^[2] However, some youth reach puberty earlier or later than expected.
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Americas are the lands of the Western hemisphere or New World consisting of the continents of North America^[1] and South America with their associated islands and regions. The Americas cover 8.3% of the Earth's total surface area (28.
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Africa is the world's second-largest and second most-populous continent, after Asia. At about 30,221,532 km² (11,668,545 sq mi) including adjacent islands, it covers 6% of the Earth's total surface area, and 20.4% of the total land area.
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Asia is the world's largest and most populous continent. It covers 8.6% of the Earth's total surface area (or 29.4% of its land area) and, with almost 4 billion people, it contains more than 60% of the world's current human population.
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Oceania (sometimes Oceanica) is a geographical, often geopolitical, region consisting of numerous lands—mostly islands in the Pacific Ocean and vicinity. The exact scope of Oceania is defined variously, with interpretations often including Australia, New Zealand, New
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World Health Organization (WHO) is a specialized agency of the United Nations (UN) that acts as a coordinating authority on international public health. Established on 7 April 1948, and headquartered in Geneva, Switzerland, the agency inherited the mandate and resources of
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19th century - 20th century - 21st century
1920s 1930s 1940s - 1950s - 1960s 1970s 1980s
1951 1952 1953 - 1954 - 1955 1956 1957

Year 1954 (MCMLIV
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19th century - 20th century - 21st century
1930s 1940s 1950s - 1960s - 1970s 1980s 1990s
1960 1961 1962 - 1963 - 1964 1965 1966

Year 1963 (MCMLXIII
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Penicillin (sometimes abbreviated PCN) is a group of beta-lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms.
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Erythromycin is a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins.
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