Information about Selection Pressure

Evolutionary pressure or selection pressure can be formalized as an external pressure applied to a process, thereby pushing that process in a distinct direction.

A process driven by evolutionary pressure is, for example, the natural selection for erythrocytes carrying the sickle cell hemoglobin gene mutation (Hb S)—causing sickle cell anaemia—in areas where malaria is a major health concern, which grants some resistance to this infectious disease. Therefore, the concept can be described as the application of Charles Darwin's principle of "survival of the fittest" (which actually should be understood as "extinction of the un-fittest") via some selection mechanism.

It is a quantitative description of the amount of change occurring in processes investigated by evolutionary biology, but the formal concept is often extended to other areas of research.

In population genetics, selection pressure is usually expressed as a selection coefficient.


Natural selection is the process by which favorable traits that are heritable become more common in successive generations of a population of reproducing organisms, and unfavorable traits that are heritable become less
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Red blood cells are the most common type of blood cell and the vertebrate body's principal means of delivering oxygen from the lungs or gills to body tissues via the blood.
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Sickle cells
Classification & external resources

Sickle-shaped red blood cells
ICD-10 D 57.
ICD-9 282.6

OMIM 603903
DiseasesDB 1206
MedlinePlus 000527
eMedicine emerg/26  

MeSH C15.378.071.141.150.
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Hemoglobin, also spelled haemoglobin and abbreviated Hb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of the blood in vertebrates and other animals.
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A gene is a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions.
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mutations are changes to the base pair sequence of the genetic material of an organism. Mutations can be caused by copying errors in the genetic material during cell division, by exposure to ultraviolet or ionizing radiation, chemical mutagens, or viruses, or can occur deliberately
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HB may refer to:
  • HB (car)
  • HB (cigarette), a German brand of cigarettes.
  • HB Ice Cream, an Irish ice cream
  • Hanna-Barbera, also known as H-B, a cartoon studio, later renamed Cartoon Network Studios
  • HB Bearings, a British bearing manufacturer
HB
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Sickle cells
Classification & external resources

Sickle-shaped red blood cells
ICD-10 D 57.
ICD-9 282.6

OMIM 603903
DiseasesDB 1206
MedlinePlus 000527
eMedicine emerg/26  

MeSH C15.378.071.141.150.
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Malaria
Classification & external resources

Plasmodium falciparum ring-forms and gametocytes in human blood.
ICD-10 B 50.
ICD-9 084

OMIM 248310
DiseasesDB 7728
MedlinePlus 000621
eMedicine med/1385   emerg/305 ped/1357
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Charles Robert Darwin

At the age of 51, Charles Darwin had just published On the Origin of Species.
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selection. Under selection, individuals with advantageous or "adaptive" traits tend to be more successful than their peers reproductively--meaning they contribute more offspring to the succeeding generation than others do.
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Evolutionary biology is a sub-field of biology concerned with the origin and descent of species, as well as their change, multiplication, and diversity over time.
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Population genetics is the study of the allele frequency distribution and change under the influence of the four evolutionary forces: natural selection, genetic drift, mutation and gene flow. It also takes account of population subdivision and population structure in space.
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In population genetics, selection coefficient is the fitness deviation, measuring the intensity of natural selection acting on the genotypes in the population. It is often denoted by the letter s.

See also

  • Evolutionary pressure

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