Information about Pneumocytes
The alveoli are lined with two types of cell, the Type I and Type II pneumocytes.
The Type II pneumocyte can replicate in the alveoli and will replicate to replace damaged Type I pneumocytes.
Granularity is a measure of the size of the components, or descriptions of components, that make up a system.
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Type I
The Type I pneumocyte is a very large, thin cell stretched over a very large area. This cell cannot replicate and is susceptible to a large number of toxic insults. Type I pneumocytes are responsible for gas exchange occurring in the alveoli.Type II
The Type II granular pneumocyte is a roughly cuboidal cell that is usually found at the alveolar septal junctions. Type II cells cover about 5% of the surface area of the alveoli, whereas type I pneumocytes (because of their squamous shape) cover 95% of the total area. Even though they cover less surface area, type II cells greatly outnumber type I cells. Type II cells are responsible for the production and secretion of surfactant.The Type II pneumocyte can replicate in the alveoli and will replicate to replace damaged Type I pneumocytes.
See also
External links
- p_25/12650572 at Dorland's Medical Dictionary
- Histology at KUMC resp-resp17 - "Alveoli"
- Histology at BU 13905loa
- Electron micrograph at luc.edu
- Electron micrographs at buffalo.edu
alveolus (plural: alveoli, from Latin alveus, "little cavity"), is an anatomical structure that has the form of a hollow cavity. Mainly found in the lung, the pulmonary alveoli
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toxin (Greek: τοξικόν, toxikon, lit. (poison) for use on arrows) is a poisonous substance produced by living cells or organisms.
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Gas exchange or respiration takes place at a respiratory surface - a boundary between the external environment and the interior of the body. For unicellular organisms the respiratory surface is simply the cell membrane, but for large organisms it usually is carried out in
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- ''See also: grain and film grain (disambiguation)
Granularity is a measure of the size of the components, or descriptions of components, that make up a system.
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Cuboidal epithelia are cube-shaped epithelial cells present in single layers (Simple cuboidal epithelium) or multiple layers (Stratified cuboidal epithelium), depending on their location in the body.
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Surfactants, also known as tensides, are wetting agents that lower the surface tension of a liquid, allowing easier spreading, and lower the interfacial tension between two liquids.
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The alveolar-capillary barrier (or membrane, or blood-air barrier) exists in the gas exchanging region of the lungs. It exists to prevent air bubbles from forming in the blood, and from blood entering the alveoli.
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A dust cell (or alveolar macrophage) is a type of macrophage found in the pulmonary alveolus, near the pneumocytes, but separated from the wall.
Activity of the dust cells is relatively high, because they are located at one of the major boundaries between the body and
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Activity of the dust cells is relatively high, because they are located at one of the major boundaries between the body and
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Dorland's is the brand name of several different medical dictionaries and ancillary products, chiefly Dorland's Illustrated Medical Dictionary (currently in its 31st edition) and Dorland's Pocket Medical Dictionary (currently in its 27th edition).
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University of Kansas (often referred to as KU or just Kansas) is an institution of higher learning in Lawrence, Kansas. The main campus resides atop Mount Oread. The University was founded in 1865 by the citizens of Lawrence under a charter from the Kansas Legislature.
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Boston University (BU) is a private research university located in Boston, Massachusetts, United States. Although chartered by the Massachusetts Legislature in 1869, Boston University traces its roots to the establishment of the Newbury Biblical Institute in Newbury,
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