Information about Ossification

Ossification is the process of bone formation, in which connective tissues, such as cartilage are turned to bone or bone-like tissue. The ossified tissue is invaginated with blood vessels. These blood vessels bring minerals like calcium and deposit it in the ossifying tissue. It is thought that this process led to bone as a structural element in vertebrates. Minerals were deposited in cartilage, which was used for storage. Bone was thus an exaptation from the ossified cartilage. It is the process in which the bone is formed.

Types of ossification

Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals.
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Cartilage is a type of dense connective tissue. It is composed of collagen fibers and/or elastin fibers, and can supply smooth surfaces for the movement of articulating bones.
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A mineral is a naturally occurring substance formed through geological processes that has a characteristic chemical composition, a highly ordered atomic structure and specific physical properties.
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Calcium (IPA: /ˈkalsiəm/) is the chemical element in the periodic table that has the symbol Ca and atomic number 20. It has an atomic mass of 40.078.
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Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals.
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Vertebrata
Cuvier, 1812

Classes and Clades

See below
Vertebrates are members of the subphylum Vertebrata (within the phylum Chordata), specifically, those chordates with backbones or spinal columns.
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A mineral is a naturally occurring substance formed through geological processes that has a characteristic chemical composition, a highly ordered atomic structure and specific physical properties.
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Cartilage is a type of dense connective tissue. It is composed of collagen fibers and/or elastin fibers, and can supply smooth surfaces for the movement of articulating bones.
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Exaptation, cooption, and preadaptation are related terms pertaining to shifts in the function of a trait. At one point the trait evolved because it served one function but subsequently it evolved because it served another function.
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Cartilage is a type of dense connective tissue. It is composed of collagen fibers and/or elastin fibers, and can supply smooth surfaces for the movement of articulating bones.
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Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals.
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Endochondral ossification is one of two types of bone formation (ossification) and is the process responsible for much of the bone growth in vertebrate skeletons, especially in long bones.
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Intramembranous ossification is one of two types of bone formation and is the process responsible for the development of flat bones, especially those found in the skull and clavicles. Unlike endochondral ossification, cartilage is not involved or present in this process.
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Mesenchyme (also known as embryonic connective tissue) is the mass of tissue that develops mainly from the mesoderm (the middle layer of the trilaminar germ disc) of an embryo. Viscous in consistency, mesenchyme contains collagen bundles and fibroblasts.
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skull is a bony structure found in many animals which serves as the general framework for the head. The skull supports the structures of the face and protects the head against injury.

The skull can be subdivided into two parts: the cranium and the mandible.
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Heterotopic ossification (HO) is the process by which trabecular bone forms outside of the skeleton.

See also

  • Myositis ossificans

References

  • Duke Orthopedics heterotopic_ossification
  • pmr/112 at eMedicine

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Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals.
..... Click the link for more information.
Cartilage is a type of dense connective tissue. It is composed of collagen fibers and/or elastin fibers, and can supply smooth surfaces for the movement of articulating bones.
..... Click the link for more information.
Cartilage is a type of dense connective tissue. It is composed of collagen fibers and/or elastin fibers, and can supply smooth surfaces for the movement of articulating bones.
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A chondroblast is a cell which originates from a mesenchymal stem cell and forms chondrocytes, commonly known as cartilage cells.

External links

  • chondroblast at eMedicine Dictionary


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Chondrocytes (from Greek chondros cartilage + kytos cell) are the only cells found in cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans.
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The perichondrium is a layer of dense irregular connective tissue which surrounds the cartilage of developing bone. It consists of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibers.
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Hyaline cartilage consists of a slimy mass of a firm consistency, but of considerable elasticity and pearly bluish color. It contains no nerves or blood vessels, and its structure is relatively simple.
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Elastic cartilage is a type of cartilage present in the outer ear, larynx, and epiglottis which contains fibers made of elastin.

Elastic cartilage, histologically is similar to hyaline cartilage but contains a plethora of elastic fibers.
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White fibrocartilage consists of a mixture of white fibrous tissue and cartilaginous tissue in various proportions; to the former of these constituents it owes its flexibility and toughness, and to the latter its elasticity.
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A fibrocartilage callus is a temporary formation of fibroblasts and chondroblasts which forms at the area of a bone fracture as the bone attempts to heal itself. The cells eventually dissipate and become dormant, laying in the resulting extracellular matrix that is the new bone.
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The metaphysis is the portion of a long bone between the epiphyses and the diaphysis. The "growth plate", or "physis", or "epiphyseal plate", although it precedes the development of the ossified metaphysis, may also be referred to as the metaphysis.
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Bones are rigid organs that form part of the endoskeleton of vertebrates. They function to move, support, and protect the various organs of the body, produce red and white blood cells and store minerals.
..... Click the link for more information.
Intramembranous ossification is one of two types of bone formation and is the process responsible for the development of flat bones, especially those found in the skull and clavicles. Unlike endochondral ossification, cartilage is not involved or present in this process.
..... Click the link for more information.
Endochondral ossification is one of two types of bone formation (ossification) and is the process responsible for much of the bone growth in vertebrate skeletons, especially in long bones.
..... Click the link for more information.


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