Information about Organ Hypertrophy


Classification & external resources
MeSHD006984
Hypertrophy is the increase of the size of an organ or in a select area of the tissue. It should be distinguished from hyperplasia which occurs due to cell division increasing the number of cells while their size stays the same; hypertrophy occurs due to an increase in the size of cells, while the number stays the same.

Examples of Hypertrophy

Muscular hypertrophy

Main article: Muscle hypertrophy
One of the most common and visible forms of organ hypertrophy occurs in skeletal muscles in response to strength training (known as muscle hypertrophy). Depending on the type of training, the hypertrophy can occur through increased sarcoplasmic volume or increased contractile proteins.

Ventricular hypertrophy

Ventricular hypertrophy is the increase in size of the ventricles of the heart. Changes can be beneficial or healthy if they occur in response to aerobic or anaerobic exercise, but ventricular hypertrophy is generally associated with pathological changes due to high blood pressure or other disease states.

Hypertrophy of breast

Main article: gigantomastia
Gigantomastia is the extreme growth of the breasts, i.e. 10 pounds per breast and more. In severe cases it is possible for women to have breasts that weigh well in excess of 20 lb each. Gigantomastia can occur as a rare complication of pregnancy, but also with the more frequently juvenile gigantomastia during puberty (virginal breast hypertrophy).

External links

Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed
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Hyperplasia (or "hypergenesis") is a general term referring to the proliferation of cells within an organ or tissue beyond that which is ordinarily seen. Hyperplasia may result in the gross enlargement of an organ, the formation of a benign tumor, or may be visible only under a
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Strength training is the use of resistance to muscular contraction to build the strength, anaerobic endurance and size of skeletal muscles. There are many different methods of strength training, the most common being the use of gravity or elastic/hydraulic forces to oppose muscle
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This article or section may contain original research or unverified claims.
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The Sarcoplasm of a muscle fiber is comparable to the cytoplasm of other cells, but it houses unusually large amounts of glycosomes (granules of stored glycogen) and significant amounts of myoglobin, an oxygen binding protein.
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The sliding filament mechanism is a process used by muscles to contract.

Process of Movement

Myosin is a molecular motor that acts like an active ratchet. Chains of actin proteins form high tensile passive 'thin' filaments that transmit the force generated by myosin to the
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Ventricular hypertrophy
Classification & external resources

ICD-10 I 51.7
ICD-9 429.3

Although ventricular hypertrophy may occur in either the left or right or both ventricles of the heart, left ventricular hypertrophy (LVH) is more commonly
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Ventricular hypertrophy
Classification & external resources

ICD-10 I 51.7
ICD-9 429.3

Although ventricular hypertrophy may occur in either the left or right or both ventricles of the heart, left ventricular hypertrophy (LVH) is more commonly
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In the heart, a ventricle is a heart chamber which collects blood from an atrium (another heart chamber that is smaller than a ventricle) and pumps it out of the heart.
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heart is a muscular organ responsible for pumping blood through the blood vessels by repeated, rhythmic contractions, or a similar structure in the annelids, mollusks, and arthropods.
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Aerobic exercise refers to exercise that is of moderate intensity, undertaken for a long duration. Aerobic means "with oxygen", and refers to the use of oxygen in a muscle's energy-generating process.
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Anaerobic exercise is typically used by athletes in non-endurance sports to build power and by body builders to build muscle mass. Muscles that are trained under anaerobic conditions develop biologically differently giving them greater performance in short duration-high intensity
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Hypertension
Classification & external resources

ICD-10 I 10. ,I 11. ,I 12. ,
I 13. ,I 15.
ICD-9 401.x

OMIM 145500
DiseasesDB 6330
MedlinePlus 000468
eMedicine med/1106   ped/1097 emerg/267


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Gigantomastia is extreme growth of the breasts, i.e. 10 pounds per breast and more. Gigantomastia was first described in literature in 1648.[1] The condition is caused by over-sensitivity to the female hormones estrogen and progesterone, and/or an unusually high quantity
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Gigantomastia is extreme growth of the breasts, i.e. 10 pounds per breast and more. Gigantomastia was first described in literature in 1648.[1] The condition is caused by over-sensitivity to the female hormones estrogen and progesterone, and/or an unusually high quantity
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Pregnancy is the carrying of one or more offspring, known as a fetus or embryo, inside the body of a female mammal such as a human. In a pregnancy, there can be multiple gestations (for example, in the case of twins or triplets).
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Puberty refers to the process of physical changes by which a child's body becomes an adult body capable of reproduction. Puberty is initiated by hormone signals from the brain to the gonads (the ovaries and testes).
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Virginal breast hypertrophy (VBH) is not a medical name, but the more known name for juvenile macromastia and juvenile gigantomastia. It causes excessive growth of the breasts during puberty and has a much higher frequency than the rare cases of breast hypertrophy in pregnancy.
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