Information about Organ Donation
Organ donation is the removal of the tissues of the human body from a person who has recently died, or from a living donor, for the purpose of transplanting or grafting them into other persons. Organs and tissues are removed in procedures similar to surgery, and all incisions are closed at the conclusion of the surgery. Steps are taken to provide a traditional funeral viewing so that people will not know the deceased was a donor. People of all ages may be organ and tissue donors. See "organ transplant" for discussion of the mechanics and history of organ transplantation.
In numerical terms, donations from dead donors far outweigh donations by living ones. The laws of different countries allow either the potential organ donor to consent or dissent to the donation during his life time, or his relatives to consent or dissent. Due to these different legislative possibilities, the number of donations per million people varies substantially in different countries.
The following tissues can be procured: bones, tendons, corneas, heart valves, femoral veins, great saphenous veins, small saphenous veins, pericardium, skin grafts, and the sclera (the tough, white outer coating surrounding the eye). These are only procured after someone has died.
Organs that can be donated from living donors include the lung, partial liver or pancreas and the kidney.
Precise regulations vary by country or even hospital to hospital. In most countries, organs are not accepted from a person who has an active or recent case of cancer (except a brain tumor which has not spread or certain mild kinds of skin cancer), who has ever had a blood cancer, or who has certain infectious diseases, including HIV or severe bacterial or fungal infections at the time of death. [2] People with these conditions may be able to donate their bodies or tissues for lab research or education, but not to a living donor. Because most people die from infections, cancer, or organ failure, only 1% of people who die at a hospital will be able to donate their organs.
At least one case of a brain tumor being spread through liver transplant has been documented. [3] However, transplant officials are reluctant to shrink the supply of organs because of this rare risk.
Some countries have proposed that HIV+ people be able to donate organs to other HIV+ people under some circumstances.
The different legislative approaches are the main reason that countries like Spain (27 donors per million inhabitants) or Austria (24 donors per million inhabitants) have higher donor rates than Germany (13 donors) or Greece (6 donors). In most countries with the dissent solutions, there is no waiting list for donations, or the list is short, while most countries with consent solutions have substantial organ shortages.
Under United States law, the regulation of organ donation is left to states within the limitations of the federal National Organ Transplant Act of 1968. Each state's Uniform Anatomical Gift Act seeks to streamline the process and standardize the rules among the various states, but it still requires that the donor make an affirmative statement during her or his lifetime that she or he is willing to be an organ donor. Many states have sought to encourage the donations to be made by allowing the consent to be noted on the driver's license. Still, it remains a pure consent system rather than an extended consent system or even a dissent opt-out system. Curiously, though, relatives can still dissent even in the presence of evidence of explicit consent by the potential organ donor (driver's licence, living will, registry information, etc.). As such, many organ donation campaigns in the United States encourage family communication about one's decision to donate or not to donate.
From a philosophical standpoint, the primary issues surrounding the morality of organ donation are semantical in nature. The debate over the definition of life, death, human, and body is ongoing. For example, whether or not a brain-dead patient ought to be kept artificially animate in order to preserve organs for harvesting is an ongoing problem in clinical bioethics.
Jewish medical ethics takes a unique approach. It accepts organ donation as a meritorious charitable act, but with two conditions: that the donor be deceased before removal of the organ and that the organ be treated respectfully (and not, for instance, merely discarded if it for some reason becomes unusable). The ethical problem stems from a lack of consensus on the definition of "deceased." According to the strictest interpretation of halachah, "deceased" means the cessation of all brain stem activity. For most organs, this point is too late for the donation to be medically useful; nevertheless, for the adherent to this view, any prior removal would be tantamount to murder. Given the nature of the market for donated organs, the second condition would limit donation to a case where there is a known and ready need for that specific organ. Alternatively, a promise can be made to ensure a proper burial for a donated organ in the event that it is not transplanted. A movement to promote organ donation from Jews to the general population in consonance with halachah has been spearheaded by the Halachic Organ Donor Society.
Further, the use of cloning to produce organs with an identical genotype to the recipient has issues all its own. Cloning is still a controversial topic, more so when the clone is created with the express purpose of being destroyed for harvesting. While the benefit of such a cloned organ is a zero-percent chance of transplant rejection, the ethical issues involved with creating and killing a clone may outweigh these benefits.
A relatively new field of transplantation has reinvigorated the debate. Xenotransplantation, or the transfer of animal (usually pig) organs into human bodies, promises to eliminate many of the ethical issues while creating many of its own. While xenotransplantation promises to increase supply of organs considerably, the threat of organ transplant rejection and the risk of xenozoonosis, coupled with the general anathema to the idea decreases the functionality of the technique. Some animal rights groups oppose the sacrifice of an animal for organ donation and have launched campaigns to ban them.
Organ donation is fast becoming an important bioethical issue from a social perspective as well. While most first-world nations have a legal system of oversight for organ transplantation, the fact remains that demand far outstrips supply. Consequently, there has arisen a black market often referred to as transplant tourism.
The issues are weighty and controversial. On the one hand are those who contend that those who can afford to buy organs are exploiting those who are desperate enough to sell their organs. Many suggest this results in a growing inequality of status between the rich and the poor. On the other hand are those who contend that the desperate should be allowed to sell their organs, and that stopping them is merely contributing to their status as impoverished. Further, those in favor of the trade hold that exploitation is morally preferable to death, and insofar as the choice lies between abstract notions of justice on the one hand and a dying person desperately in need of an organ on the other hand, the organ trade should be legalized. Conversely, surveys conducted among living donors postoperatively and in a period of five years following the procedure have shown an extreme regret in a majority of the donors who said that given the chance to repeat the procedure, they would not [4]. Additionally, many study participants reported a decided worsening of economic condition following the procedure [5]
Legalization of the organ trade carries with it its own sense of justice as well. Continuing black-market trade creates further disparity on the demand side: only the rich can afford such organs. Legalization of the international organ trade could lead to increased supply, lowering prices so that persons outside the welathiest segments could afford such organs as well.
Exploitation arguments generally come from two main areas:
Faith in the medical system is important to the success of organ donation. Brazil switched to an opt-out system and ultimately had to withdraw it because it further alienated patients who already distrusted the country's medical system. [12]
Adequate funding, strong political will to see transplant outcomes improve, and the existence of specialized training, care and facilities also increase donation rates. Expansive legal definitions of death, such as Spain uses, also increase the pool of eligible donors by allowing physicians to declare a patient to be dead at an earlier stage, when the organs are still in good physical condition.
Allowing or forbidding payment for organs affects the availability of organs. Generally, where organs can not be bought or sold, quality and safety are high, but supply is not adequate to the demand. Where organs can be purchased, the supply increase somewhat, but safety declines, as families and living donors have an incentive to conceal unfavorable information.
Some political decisions have unintended consequences for donation rates. For example, motorcycle helmet laws and drunk driving laws have lowered the number of sudden deaths in vehicle accidents, and therefore lowered the number of otherwise healthy corpses which could have been organ donors.
Healthy humans have two kidneys, a redundancy that enables living donors (inter vivos) to give a kidney to someone who needs it. The most common transplants are to close relatives, but people have given kidneys to other friends. The rarest type of donation is the undirected donation whereby a donor gives a kidney to a stranger. Less than a few hundred of such kidney donations have been performed. In recent years, searching for "good Samaritan" donors via the internet has also become a way to find life saving organs.
The Spanish transplant system is one of the most successful in the world, but it still can't meet the demand, as 10% of those needing a transplant die while still on the transplant list.[13] Donations from corpses are anonymous, and a network for communication and transport allows fast extraction and transplant across the country. Under Spanish law, every corpse can provide organs unless the deceased person expressly rejected it. Because family members still can forbid the donation,[14] carefully trained doctors ask the family for permission, making it very similar in practice to the United States system.[15]
In the overwhelming majority of cases, organ donation is not possible for reasons of recipient safety, match failures, or organ condition. Even in Spain, which has the highest organ donation rate in the world, there are only 35.1 actual donors per million people, and there are hundreds of patients on the waiting list. [16] This rate compares to 24.8 per million in Austria, where families are rarely asked to donate organs, and 22.2 per million in France, which -- like Spain -- has a presumed-consent system and routinely asks families for the gift of life.
Approaches to addressing this shortfall include:
A concern which many people have about organ donation is that the quality of care which a potential donor may receive may be affected by the arrest and charging of Dr. Roozrokh. Dr. Timothy Pruett, president-elect of the United Network for Organ Sharing UNOS, called the allegations 'horrific.'
In addition, he worried that they could scare people away from donating organs to help the 95,000 people awaiting life-saving transplants nationwide. UNOS is the federal contractor charged with ensuring the safety and equity of the nation's transplant system. 'We have to guarantee to the public that we're not going to go out and kill people to get their organs,' said Pruett, chief of transplant surgery at the University of Virginia. 'That's the worst of those cheap sci-fi books: 'The ghoulish docs are out pulling the plugs on these poor defenseless people, trying to snatch their organs.'
Classification & external resources
ICD-10 B20-B24
ICD-9 042 - 044
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In numerical terms, donations from dead donors far outweigh donations by living ones. The laws of different countries allow either the potential organ donor to consent or dissent to the donation during his life time, or his relatives to consent or dissent. Due to these different legislative possibilities, the number of donations per million people varies substantially in different countries.
Organs and tissues which can be donated
Organs that can be procured include:[1] the heart, intestines, kidneys, lungs, liver, pancreas. These are procured from a brain dead donor or a donor where the family has consent for donation after cardiac death also known as DCD. This is where the donor has not progressed to brain death.The following tissues can be procured: bones, tendons, corneas, heart valves, femoral veins, great saphenous veins, small saphenous veins, pericardium, skin grafts, and the sclera (the tough, white outer coating surrounding the eye). These are only procured after someone has died.
Organs that can be donated from living donors include the lung, partial liver or pancreas and the kidney.
Recipient protection
To protect the person receiving an organ, various health and safety tests are conducted. Because an organ transplant requires immune suppression, it is important that the organ not be infected with a disease that could harm the recipient.Precise regulations vary by country or even hospital to hospital. In most countries, organs are not accepted from a person who has an active or recent case of cancer (except a brain tumor which has not spread or certain mild kinds of skin cancer), who has ever had a blood cancer, or who has certain infectious diseases, including HIV or severe bacterial or fungal infections at the time of death. [2] People with these conditions may be able to donate their bodies or tissues for lab research or education, but not to a living donor. Because most people die from infections, cancer, or organ failure, only 1% of people who die at a hospital will be able to donate their organs.
At least one case of a brain tumor being spread through liver transplant has been documented. [3] However, transplant officials are reluctant to shrink the supply of organs because of this rare risk.
Some countries have proposed that HIV+ people be able to donate organs to other HIV+ people under some circumstances.
Legislation regarding organ donation
There are basically four different legislative approaches to the donation, if the donor has not explicitly dissented. The least restrictive approach is the dissent solution, according to which the donor has to explicitly dissent to donation during his lifetime. According to the extended dissent solution, relatives may dissent in the event the potential donor has not consented.The different legislative approaches are the main reason that countries like Spain (27 donors per million inhabitants) or Austria (24 donors per million inhabitants) have higher donor rates than Germany (13 donors) or Greece (6 donors). In most countries with the dissent solutions, there is no waiting list for donations, or the list is short, while most countries with consent solutions have substantial organ shortages.
Under United States law, the regulation of organ donation is left to states within the limitations of the federal National Organ Transplant Act of 1968. Each state's Uniform Anatomical Gift Act seeks to streamline the process and standardize the rules among the various states, but it still requires that the donor make an affirmative statement during her or his lifetime that she or he is willing to be an organ donor. Many states have sought to encourage the donations to be made by allowing the consent to be noted on the driver's license. Still, it remains a pure consent system rather than an extended consent system or even a dissent opt-out system. Curiously, though, relatives can still dissent even in the presence of evidence of explicit consent by the potential organ donor (driver's licence, living will, registry information, etc.). As such, many organ donation campaigns in the United States encourage family communication about one's decision to donate or not to donate.
Bioethical issues in organ donation
Since the mid-1970s, bioethics, a relatively new area of ethics, has emerged at the forefront of modern clinical science. Many philosophical arguments against organ donation stem from this field. Generally, the arguments are rooted in either deontological or teleological ethical considerations.Deontological issues
Pioneered by Paul Ramsey and Leon Kass, few modern bioethicists disagree on the moral status of organ donation. Certain groups, like the Roma (gypsies), oppose organ donation on religious grounds, but most of the world's religions support donation as a charitable act of great benefit to the community. Issues surrounding patient autonomy, living wills, and guardianship make it nearly impossible for involuntary organ donation to occur. In issues relating to public health, it is possible that a compelling state interest overrules any patient right to autonomy.From a philosophical standpoint, the primary issues surrounding the morality of organ donation are semantical in nature. The debate over the definition of life, death, human, and body is ongoing. For example, whether or not a brain-dead patient ought to be kept artificially animate in order to preserve organs for harvesting is an ongoing problem in clinical bioethics.
Jewish medical ethics takes a unique approach. It accepts organ donation as a meritorious charitable act, but with two conditions: that the donor be deceased before removal of the organ and that the organ be treated respectfully (and not, for instance, merely discarded if it for some reason becomes unusable). The ethical problem stems from a lack of consensus on the definition of "deceased." According to the strictest interpretation of halachah, "deceased" means the cessation of all brain stem activity. For most organs, this point is too late for the donation to be medically useful; nevertheless, for the adherent to this view, any prior removal would be tantamount to murder. Given the nature of the market for donated organs, the second condition would limit donation to a case where there is a known and ready need for that specific organ. Alternatively, a promise can be made to ensure a proper burial for a donated organ in the event that it is not transplanted. A movement to promote organ donation from Jews to the general population in consonance with halachah has been spearheaded by the Halachic Organ Donor Society.
Further, the use of cloning to produce organs with an identical genotype to the recipient has issues all its own. Cloning is still a controversial topic, more so when the clone is created with the express purpose of being destroyed for harvesting. While the benefit of such a cloned organ is a zero-percent chance of transplant rejection, the ethical issues involved with creating and killing a clone may outweigh these benefits.
A relatively new field of transplantation has reinvigorated the debate. Xenotransplantation, or the transfer of animal (usually pig) organs into human bodies, promises to eliminate many of the ethical issues while creating many of its own. While xenotransplantation promises to increase supply of organs considerably, the threat of organ transplant rejection and the risk of xenozoonosis, coupled with the general anathema to the idea decreases the functionality of the technique. Some animal rights groups oppose the sacrifice of an animal for organ donation and have launched campaigns to ban them.
Teleological issues
On teleological or utilitarian grounds, the moral status of "black market organ donation" relies upon the ends, rather than the means. Insofar as those that donate organs are often impoverished and those that can afford black market organs are typically well-off, it would appear that there is an imbalance in the trade. In many cases, those in need of organs are put on waiting lists for legal organs for indeterminate lengths of time — many die while still on a waiting list.Organ donation is fast becoming an important bioethical issue from a social perspective as well. While most first-world nations have a legal system of oversight for organ transplantation, the fact remains that demand far outstrips supply. Consequently, there has arisen a black market often referred to as transplant tourism.
The issues are weighty and controversial. On the one hand are those who contend that those who can afford to buy organs are exploiting those who are desperate enough to sell their organs. Many suggest this results in a growing inequality of status between the rich and the poor. On the other hand are those who contend that the desperate should be allowed to sell their organs, and that stopping them is merely contributing to their status as impoverished. Further, those in favor of the trade hold that exploitation is morally preferable to death, and insofar as the choice lies between abstract notions of justice on the one hand and a dying person desperately in need of an organ on the other hand, the organ trade should be legalized. Conversely, surveys conducted among living donors postoperatively and in a period of five years following the procedure have shown an extreme regret in a majority of the donors who said that given the chance to repeat the procedure, they would not [4]. Additionally, many study participants reported a decided worsening of economic condition following the procedure [5]
Legalization of the organ trade carries with it its own sense of justice as well. Continuing black-market trade creates further disparity on the demand side: only the rich can afford such organs. Legalization of the international organ trade could lead to increased supply, lowering prices so that persons outside the welathiest segments could afford such organs as well.
Exploitation arguments generally come from two main areas:
- Physical exploitation suggests that the operations in question are quite risky, and, taking place in third-world hospitals or "back-alleys," even more risky. Yet, if the operations in question can be made safe, there is little threat to the donor.
- Financial exploitation suggests that the donor (especially in the Indian subcontinent and Africa) are not paid enough. Commonly, accounts from persons who have sold organs in both legal and black market circumstances put the prices at between $150 and $5,000, depending on the local laws, supply of ready donors and scope of the transplant operation [6], [7], [8]. In Chennai, India where one of the largest black markets for organs is known to exist, studies have placed the average sale price at little over $1,000 [9]. Many accounts also exist of donors being postoperatively denied their promised pay [10].
- The New Cannibalism is a phrase coined by anthropologist Nancy Scheper-Hughes in 1998 for an article written for The New Internationalist. Her argument was that the actual exploitation is an ethical failing, a human exploitation; a perception of the poor as organ sources which may be used to extend the lives of the wealthy.[11]
Political issues
There are also controversial issues regarding how organs are allocated between patients. For example, some believe that livers should not be given to alcoholics in danger of reversion, while others view alcoholism as a medical condition like diabetes.Faith in the medical system is important to the success of organ donation. Brazil switched to an opt-out system and ultimately had to withdraw it because it further alienated patients who already distrusted the country's medical system. [12]
Adequate funding, strong political will to see transplant outcomes improve, and the existence of specialized training, care and facilities also increase donation rates. Expansive legal definitions of death, such as Spain uses, also increase the pool of eligible donors by allowing physicians to declare a patient to be dead at an earlier stage, when the organs are still in good physical condition.
Allowing or forbidding payment for organs affects the availability of organs. Generally, where organs can not be bought or sold, quality and safety are high, but supply is not adequate to the demand. Where organs can be purchased, the supply increase somewhat, but safety declines, as families and living donors have an incentive to conceal unfavorable information.
Some political decisions have unintended consequences for donation rates. For example, motorcycle helmet laws and drunk driving laws have lowered the number of sudden deaths in vehicle accidents, and therefore lowered the number of otherwise healthy corpses which could have been organ donors.
Healthy humans have two kidneys, a redundancy that enables living donors (inter vivos) to give a kidney to someone who needs it. The most common transplants are to close relatives, but people have given kidneys to other friends. The rarest type of donation is the undirected donation whereby a donor gives a kidney to a stranger. Less than a few hundred of such kidney donations have been performed. In recent years, searching for "good Samaritan" donors via the internet has also become a way to find life saving organs.
The Spanish transplant system is one of the most successful in the world, but it still can't meet the demand, as 10% of those needing a transplant die while still on the transplant list.[13] Donations from corpses are anonymous, and a network for communication and transport allows fast extraction and transplant across the country. Under Spanish law, every corpse can provide organs unless the deceased person expressly rejected it. Because family members still can forbid the donation,[14] carefully trained doctors ask the family for permission, making it very similar in practice to the United States system.[15]
In the overwhelming majority of cases, organ donation is not possible for reasons of recipient safety, match failures, or organ condition. Even in Spain, which has the highest organ donation rate in the world, there are only 35.1 actual donors per million people, and there are hundreds of patients on the waiting list. [16] This rate compares to 24.8 per million in Austria, where families are rarely asked to donate organs, and 22.2 per million in France, which -- like Spain -- has a presumed-consent system and routinely asks families for the gift of life.
Issues specifically arising in countries that have implemented the consent solution
Organ shortfall
A persistent issue relating to organ donation is the scarcity of organ donors relative to the number of potential recipients on organ donation waiting lists. In the United States, the waiting list is quoted to be about 96,522 people long.[17] Different organs have different waiting times and success rates because demand is significantly different for different organs. Three-quarters of patients in need of an organ transplant are waiting for a kidney,[18] and more than half of them die before a matching organ becomes available.[19] This is less common with other organs. At the Oregon Health and Science University, for example, the median patient who ultimately received an organ waited only three weeks for a heart and three months for a pancreas or liver — but 476 days for a kidney, because demand for kidneys substantially outstrips supply.[20] In Australia, there are 10.8 transplants per million people, [21] about a third of the Spanish rate. The Lions Eye Institute, in Western Australia, houses the Lions Eye Bank. The Bank was established in 1986 and coordinates the collection, processing and distribution of eye tissue for transplantation. The Lions Eye Bank also maintains a waitlist of patients who require corneal graft operations. About 100 corneas are provided by the Bank for transplant each year, but there is still an extensive waiting list for corneas.[22]Approaches to addressing this shortfall include:
- donor registries and "primary consent" laws, to remove the burden of the donation decision from the legal next-of-kin
- monetary incentives for signing up to be a donor
- an opt-out system ("dissent solution"), in which a potential donor or its relatives must take specific action to be excluded from organ donation, rather than specific action to be included
- social incentive programs, wherein members sign a legal agreement to direct their organs first to other members who are on the transplant waiting list
Recent controversy in Organ Transplantation Case in California
A doctor (Hootan Roozrokh) in San Luis Obispo, California has been accused by prosecutors of prescribing excessive doses of morphine and sedatives to hasten the death of a disabled man with cerebral palsy and irreversible brain damage, in order to harvest his organs for transplant. The case being brought against Dr. Hootan Roozrokh is the first time in US medical history a transplant doctor has ever been charged in this manner.A concern which many people have about organ donation is that the quality of care which a potential donor may receive may be affected by the arrest and charging of Dr. Roozrokh. Dr. Timothy Pruett, president-elect of the United Network for Organ Sharing UNOS, called the allegations 'horrific.'
In addition, he worried that they could scare people away from donating organs to help the 95,000 people awaiting life-saving transplants nationwide. UNOS is the federal contractor charged with ensuring the safety and equity of the nation's transplant system. 'We have to guarantee to the public that we're not going to go out and kill people to get their organs,' said Pruett, chief of transplant surgery at the University of Virginia. 'That's the worst of those cheap sci-fi books: 'The ghoulish docs are out pulling the plugs on these poor defenseless people, trying to snatch their organs.'
Sources
1. ^ Which Organs Can Be Donated for Transplantation?. New York Organ Donor Network.
2. ^ [1]
3. ^ [2]
4. ^ [3]
5. ^ [4]
6. ^ [5]
7. ^ [6]
8. ^ [7]
9. ^ [8]
10. ^ [9]
11. ^ [10]
12. ^ [11]
13. ^ [12]
14. ^ [13]
15. ^ [14]
16. ^ [15]
17. ^ Organ Donation and Transplantation. United Network for Organ Sharing. Retrieved on 2007-05-29.
18. ^ [16]
19. ^ [17]
20. ^ [18]
21. ^ [19]
22. ^ [20]
2. ^ [1]
3. ^ [2]
4. ^ [3]
5. ^ [4]
6. ^ [5]
7. ^ [6]
8. ^ [7]
9. ^ [8]
10. ^ [9]
11. ^ [10]
12. ^ [11]
13. ^ [12]
14. ^ [13]
15. ^ [14]
16. ^ [15]
17. ^ Organ Donation and Transplantation. United Network for Organ Sharing. Retrieved on 2007-05-29.
18. ^ [16]
19. ^ [17]
20. ^ [18]
21. ^ [19]
22. ^ [20]
External links
- United Network for Organ Sharing
- National Institute of Health's MedLine on Organ Donation
- OrganDonor.gov
- Gift of Hope (Illinois Organ and Tissue Procurement Agency)
- Mid-America Transplant Services (Missouri Organ and Tissue Procurement Agency)
- Donor Alliance (Colorado Organ and Tissue Procurement Agency)
- Lifesharing (California Organ and Tissue Procurement Agency)
- Donate Life
- Living Donors Online
- Online Community for Dialysis Patients by Dialysis Patients
- BBC Health about UK Organ Donation
- DonateTheGiftOfLife.com
- Donate Life America
- Upstate New York Transplant Services
- New York Organ Donor Network
- Halachic Organ Donor Society
- Lifesharers
- Organs Watch
- The Initiative on Global Organ Trafficking
- Students for Organ Donation - Official Website
- Donorfind.org - Global organ donation network
Biological tissue is a collection of interconnected cells that perform a similar function within an organism.
The study of tissue is known as histology, or, in connection with disease, histopathology.
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The study of tissue is known as histology, or, in connection with disease, histopathology.
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The human body is the entire physical structure of a human organism. The human body consists of a head, neck, torso, two arms and two legs. The average height of an adult human is about 1.6 m (5 to 6 feet) tall. This size is largely determined by genes.
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Death is the permanent end of the life of a biological organism. Death may refer to the end of life as either an event or condition.[1] Many factors can cause or contribute to an organism's death, including predation, disease, habitat destruction, senescence,
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organ transplant is the moving of a whole or partial organ from one body to another (or from a donor site on the patient's own body), for the purpose of replacing the recipient's damaged or failing organ with a working one from the donor site.
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In medicine, grafting is a surgical procedure to transplant tissue without a blood supply. The implanted tissue must obtain a blood supply from the new vascular bed or otherwise die.
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surgery (from the Greek χειρουργική meaning "hand work") is the medical specialty that treats diseases or injuries by operative manual and instrumental treatment.
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This article may contain original research or unverified claims.
A funeral is a ceremony marking a person's death.
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This article has been tagged since January 2007.
This article has been tagged since January 2007.
A funeral is a ceremony marking a person's death.
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organ transplant is the moving of a whole or partial organ from one body to another (or from a donor site on the patient's own body), for the purpose of replacing the recipient's damaged or failing organ with a working one from the donor site.
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heart is a muscular organ responsible for pumping blood through the blood vessels by repeated, rhythmic contractions, or a similar structure in the annelids, mollusks, and arthropods.
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In anatomy, the intestine is the segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine.
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The kidneys are organs that filter wastes (such as urea) from the blood and excrete them, along with water, as urine. The medical field that studies the kidneys and diseases of the kidney is called nephrology[1].
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lungs flank the heart and great vessels in the chest cavity.[1]]]
The lung is the essential respiration organ in air-breathing vertebrates, the most primitive being the lungfish.
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The lung is the essential respiration organ in air-breathing vertebrates, the most primitive being the lungfish.
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liver is an organ present in vertebrates and some other animals. It plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, and detoxification.
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The pancreas is a gland organ in the digestive and endocrine systems of vertebrates<ref name="New Standard" />. It is both exocrine (secreting pancreatic juice containing digestive enzymes) and endocrine (producing several important hormones, including
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Brain death is a legal definition of death that emerged in the 1960's as a response to the ability to resuscitate individuals and mechanically keep the heart and lungs working. In simple terms, brain death is the irreversible end of all brain activity.
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DCD is a three-letter abbreviation with multiple meanings, including:
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- Data Carrier Detect, a term used with modems. Also see RS-232.
- Dead Can Dance is an originally Australian eclectic band, popular among goth music listeners.
- Def Con Dos is a Spanish rap metal band.
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Brain death is a legal definition of death that emerged in the 1960's as a response to the ability to resuscitate individuals and mechanically keep the heart and lungs working. In simple terms, brain death is the irreversible end of all brain activity.
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Bone grafting is a surgical procedure that replaces missing bone with material from the patient's own body, an artificial, synthetic, or natural substitute. Bone grafting is used to repair bone fractures that are extremely complex, pose a significant risk to the patient, or fail to
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A tendon (or sinew) is a tough band of fibrous connective tissue that connects muscle to bone and is built to withstand tension. Tendons are similar to ligaments except that ligaments join one bone to another.
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The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber, providing most of an eye's optical power.[1] Together with the lens, the cornea refracts light, and as a result helps the eye to focus, accounting for approximately
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In anatomy, the heart valves are valves in the heart that maintain the unidirectional flow of blood by opening and closing depending on the difference in pressure on each side. The mechanical equivalent of the heart valves would be the reed valves.
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In the human body, the femoral vein is a blood vessel that accompanies the femoral artery in the femoral sheath. It begins at the adductor canal (also known as Hunter's canal) and is a continuation of the popliteal vein.
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The great saphenous vein, also greater saphenous vein, is the large (subcutaneous) superficial vein of the leg and thigh.
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Path
It originates from where the dorsal vein of the first digit (the large toe) merges with the dorsal venous arch of the foot...... Click the link for more information.
The small saphenous vein (also lesser saphenous vein), is a relatively large vein of the superficial posterior leg.
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Path
Its origin is where the dorsal vein from the fifth digit (smallest toe) merges with the dorsal venous arch of the foot, which attaches to the..... Click the link for more information.
The pericardium is a double-walled sac that contains the heart and the roots of the great vessels.
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Layers
There are two layers to this sac: the fibrous pericardium and the serous pericardium...... Click the link for more information.
Skin grafting is a type of medical grafting involving the transplantation of skin. The transplanted tissue is called a skin graft.
Skin grafting is often used to treat:
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Skin grafting is often used to treat:
- Extensive wounding or trauma
- Burns
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The sclera is the opaque (usually white), fibrous, protective layer of the eye containing collagen and elastic fibers.[1] In children, it is thinner and shows some of the underlying pigment, appearing slightly blue.
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Death is the permanent end of the life of a biological organism. Death may refer to the end of life as either an event or condition.[1] Many factors can cause or contribute to an organism's death, including predation, disease, habitat destruction, senescence,
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Intervention:
ICD-10 code:
ICD-9 code: 52.8
Other codes: A pancreas transplant is an organ transplant that involves implanting a healthy pancreas (one that can produce insulin) into a person who has diabetes.
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ICD-10 code:
ICD-9 code: 52.8
Other codes: A pancreas transplant is an organ transplant that involves implanting a healthy pancreas (one that can produce insulin) into a person who has diabetes.
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- Human immunodeficiency virus 1
- Human immunodeficiency virus 2
Classification & external resources
ICD-10 B20-B24
ICD-9 042 - 044
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Herod_Archelaus
