Information about Muscular System

The muscular system is the biological system of an organism that allows it to move. The muscular system in vertebrates is controlled through the nervous system, although some muscles (such as the cardiac muscle) can be completely autonomous.

Muscles

Main article: Muscle


There are distincts types of muscles: skeletal muscles, heart muscles and smooth muscles.

Skeletal muscle

Main article: Skeletal muscle
Enlarge picture
Bodybuilder showing macrostructure of muscular system.


Skeletal muscle fibers are multinucleated, with the cell's nuclei located just beneath the plasma membrane. The cell comprises a series of striped or striated, thread-like myofibrils. Within each myofibril there are protein filaments that are anchored by dark Z lines. The fibre is one long continuous thread-like structure. The smallest cross section of skeletal muscle is called a sarcomere which is the functional unit within the cell. It extends from one Z line to the next attached Z line. The individual sarcomere has alternating thick myosin and thin actin protein filaments. Myosin forms the center or middle of each sarcomere. The exact center of the sarcomere is designated the M line. Thinner actin filaments form a zig zag pattern along the anchor points or Z line.

Upon stimulation by an action potential, skeletal muscles perform a coordinated contraction by shortening each sarcomere. The best proposed model for understanding contraction is the sliding filament model of muscle contraction. Actin and myosin fibers overlap in a contractile motion towards each other. Myosin filaments have club-shaped heads that project toward the actin filaments.

Larger structures along the myosin filament called myosin heads are used to provide attachment points on binding sites for the actin filaments. The myosin heads move in a coordinated style, they swivel toward the center of the sarcomere, detach and then reattach to the nearest active site of the actin filament. This is called a rachet type drive system. This process consumes large amounts of adenosine triphosphate (ATP).

Energy for this comes from ATP, the energy source of the cell. ATP binds to the cross bridges between myosin heads and actin filaments. The release of energy powers the swiveling of the myosin head. Muscles store little ATP and so must continuously recycle the discharged adenosine diphosphate molecule (ADP) into ATP rapidly. Muscle tissue also contains a stored supply of a fast acting recharge chemical, creatine phosphate which can assist initially producing the rapid regeneration of ADP into ATP.

Calcium ions are required for each cycle of the sarcomere. Calcium is released from the sarcoplasmic reticulum into the sarcomere when a muscle is stimulated to contract. This calcium uncovers the actin binding sites. When the muscle no longer needs to contract, the calcium ions are pumped from the sarcomere and back into storage in the sarcoplasmic reticulum.

Anatomy

There are approximately 639 skeletal muscles in the human body.

The following are some major muscles[1] and their basic features:

MuscleOriginInsertionArteryNerveActionAntagonist
gastrocnemiusfemurcalcaneussural arteriestibial nerveplantarflexion, flexion of knee (minor)Tibialis anterior muscle
tibialis posteriortibia, fibulaFootposterior tibial arterytibial nerveinversion of the foot, plantar flexion of the foot at the ankleTibialis anterior muscle
soleusfibula, medial border of tibiacalcaneussural arteriestibial nerveplantarflexionTibialis anterior muscle
tibialis anteriortibiafootanterior tibial artery Fibular nervedorsiflex and invert the footFibularis longus, Gastrocnemius, Soleus, Plantaris, Tibialis posterior
longusfibulaFootfibular arterySuperficial fibular nerveplantarflexion, eversionTibialis anterior muscle
brevisfibulaFoot, eversionperoneal arterysuperficial peroneal nerve
gluteus maximus muscleilium, sacrum, sacrotuberous ligamentGluteal tuberosity of the femurgluteal arteriesinferior gluteal nerveexternal rotation and extension of the hip jointIliacus, Psoas major, Psoas minor
biceps femorisischium, femurfibulainferior gluteal artery, popliteal arterytibial nerve, common peroneal nerveflexes and laterally rotates knee joint, extends hip jointQuadriceps muscle
semitendinosusischiumtibiainferior gluteal arterysciaticflex knee, extend hip jointQuadriceps muscle
semimembranosusischiumtibiaprofunda femoris, gluteal arterysciatic nerveHip extension, Knee flexionQuadriceps muscle
Iliopsoasiliumfemurmedial femoral circumflex artery, iliolumbar arteryfemoral nerve, lumbar nervesflexion of hipGluteus maximus, posterior compartment of thigh
quadriceps femorisscombined rectus femoris and vastus musclesfemoral arteryFemoral nerveKnee extension; Hip flexionHamstring
adductor muscles of the hippubisfemur, tibiaobturator nerveadduction of hip
levator scapulaevertebral columnscapuladorsal scapular arterycervical nerve, dorsal scapular nerveElevates scapula, tilts its glenoid cavity inferiorly
trapeziusthe rear of the skull, vertebral columnclavicle, scapulacranial nerve XI, cervical nervesretraction of scapulaSerratus anterior muscle
rectus abdominisPubisCostal cartilage of ribs 5-7, sternuminferior epigastric arterysegmentally by thoraco-abdominal nervesflexion of trunk/lumbar vertebraeErector spinae
transversus abdominisribs, iliumpubic tuberclelower intercostal nerves, iliohypogastric nerve and the ilioinguinal nervecompress the ribs and viscera, thoracic and pelvic stability
Abdominal external oblique muscleLower 8 costaeCrista iliaca, ligamentum inguinalelower 6 intercostal nerve, subcostal nerveRotates torso
Abdominal internal oblique muscleInguinal ligament, Iliac crest and the Lumbodorsal fasciaLinea alba, sternum and the inferior ribs.Compresses abdomen and rotates vertebral column.
erector spinaeon the spines of the last four thoracic vertebræboth the spines of the most cranial thoracic vertebrae and the cervical vertebraelateral sacral arteryposterior branch of spinal nerveextends the vertebral columnRectus abdominis muscle
pectoralis majorclavicle, sternum, costal cartilageshumerusthoracoacromial trunklateral pectoral nerve and medial pectoral nerveClavicular head: flexes the humerus
Sternocostal head: extends the humerus
As a whole, adducts and medially rotates the humerus. It also draws the scapula anteriorly and inferiorly.
biceps brachiiscapularadiusbrachial arteryMusculocutaneous nerveflexes elbow and supinates forearmTriceps brachii muscle
triceps brachiiscapula and humerusulnadeep brachial arteryradial nerveextends forearm, caput longum adducts shoulderBiceps brachii muscle
brachialishumerusulnaradial recurrent arterymusculocutaneous nerveflexion at elbow joint
pronator tereshumerus, ulnaradiusulnar artery and radial arterymedian nervepronation of forearm, flexes elbowSupinator muscle
brachioradialishumerusradiusradial recurrent arteryradial nerveFlexion of forearm
rhomboidsnuchal ligaments, spinous processes of the C7 to T5 vertebraescapuladorsal scapular arterydorsal scapular nerveRetracts the scapula and rotates it to depress the glenoid cavity. fixes the scapula to the thoracic wall.Serratus anterior muscle
deltoidclavicle, acromion, scapuladeltoid tuberosity of humerusprimarily posterior circumflex humeral arteryAxillary nerveshoulder abduction, flexion and extensionLatissimus dorsi
latissimus dorsivertebral column, ilium and inferior 3 or 4 ribshumerussubscapular artery, dorsal scapular arterythoracodorsal nervepulls the forelimb dorsally and caudallydeltoid, trapezius
Rotator cuffscapulahumeruslateral rotation, medial rotation, abduction

Aerobic and anerobic muscle activity

At rest, the body produces the majority of its ATP aerobically in the mitochondria without producing lactic acid or other fatiguing byproducs.[2] During exercise, the method of ATP production varies depending on the fitness of the individual as well as the duration, and intensity of exercise. At lower activity levels, when exercise continues for a long duration (several minutes or longer), energy is produced aerobically by combining oxygen with carbohydrates and fats stored in the body. Activity that is higher in intensity, with possible duration decreasing as intensity increases, ATP production can switch to anaerobic pathways, such as the use of the creatine phosphate and the phosphagen system or anaerobic glycolysis. Aerobic ATP production is biochemically much slower and can only be used for long-duration, low intensity exercise, but produces no fatiguing waste products that can not be removed immediately from sarcomere and body and results in a much greater number of ATP molecules per fat or carbohydrate molecule. Aerobic training allows the oxygen delivery system to be more efficient, allowing aerobic metabolism to being more quickly.[2] Anaerobic ATP production produces ATP much faster and allows near-maximal intensity exercise, but also produces significant amounts of lactic acid which render high intensity exercise unsustainable for greater than several minutes.[2] The phosphagen system is also anaerobic, allows for the highest levels of exercise intensity, but intramuscular stores of phosphocreatine are very limited and can only provide energy for exercises lasting up to ten seconds. Recovery is very quick, with full creatine stores regenerated within five minutes.[2]

Heart muscle

Main article: Heart muscle
Heart muscles are distinct from skeletal muscles because the muscle fibres are laterally connected to each other. Furthermore, just as with smooth muscles, they are not controlled by will. Heart muscles are controlled by the sinus node, which, in turn, is infuenced by the autonomic nervous system.

Smooth muscle

Main article: Smooth muscle
Smooth muscles are controlled directly by the autonomic nervous system.

Control of muscle contraction

Neuromuscular junctions are the focal point where a motor neuron attaches to a muscle. Acetylcholine, (a neurotransmitter used in skeletal muscle contraction) is released from the axon terminal of the nerve cell when an action potential reaches the microscopic junction, called a synapse. A group of chemical messengers cross the synapse and stimulate the formation of electrical changes, which are produced in the muscle cell when the acetylcholine binds to receptors on its surface. Calcium is released from its storage area in the cell's sarcoplasmic reticulum. An impulse from a nerve cell causes calcium release and brings about a single, short muscle contraction called a muscle twitch. If there is a problem at the neuromuscular junction, a very prolonged contraction may occur, tetanus. Also, a loss of function at the junction can produce paralysis.

Skeletal muscles are organized into hundreds of motor units, each of which involves a motor neuron, attached by a series of thin finger-like structures called axon terminals. These attach to and control discrete bundles of muscle fibers. A coordinated and fine tuned response to a specific circumstance will involve controlling the precise number of motor units used. While individual muscle units contract as a unit, the entire muscle can contract on a predetermined basis due to the structure of the motor unit. Motor unit coordination, balance, and control frequently come under the direction of the cerebellum of the brain. This allows for complex muscular coordination with little conscious effort, such as when one drives a car without thinking about the process.

See also

  • Major systems of the human body

Notes

References

External links

Vertebrata
Cuvier, 1812

Classes and Clades

See below
Vertebrates are members of the subphylum Vertebrata (within the phylum Chordata), specifically, those chordates with backbones or spinal columns.
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nervous system of an animal coordinates the activity of the muscles, monitors the organs, constructs and also stops input from the senses, and initiates actions. Prominent parts of a nervous system include neurons and nerves, which are used in coordination.
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MUSCLE (multiple sequence comparison by log-expectation) is public domain, multiple sequence alignment software for protein and nucleotide sequences.
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'Cardiac muscle' is a type of involuntary striated muscle found within the heart. Its function is to "pump" blood through the circulatory system by contracting.
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MUSCLE (multiple sequence comparison by log-expectation) is public domain, multiple sequence alignment software for protein and nucleotide sequences.
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Myocardium is the muscular tissue of the heart.

Relationship to other layers

The other tissues of the heart are:
  • the endocardium (inner lining, effectively a specialized endothelium)

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Smooth muscle is a type of non-striated muscle, found within the "walls" of hollow organs and elsewhere like the bladder and abdominal cavity, the uterus, male and female reproductive tracts, the gastrointestinal tract, the respiratory tract, the vasculature, the skin and the
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Skeletal muscle is a type of striated muscle, usually attached to the skeleton. Skeletal muscles are used to create movement, by applying force to bones and joints; via contraction.
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Myofibrils (obsolete term: sarcostyles) are cylindrical organelles, found within muscle cells. They are bundles of actomyosin filaments that run from one end of the cell to the other and are attached to the cell surface membrane at each end.
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A sarcomere is the basic unit of a muscle's cross-striated myofibril. Sarcomeres are multi-protein complexes composed of three different filament systems.
  • The thick filament system is composed of myosin protein which is connected from the M-line to the Z-disc by Titin

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Myosins are a large family of motor proteins found in eukaryotic tissues. They are responsible for actin-based motility.

Structure and Function

Domains

Most myosin molecules are composed of both a head and a tail domain.
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Actin is a globular structural, 42-47 kDa protein found in many eukaryotic cells, with concentrations of over 100 μM. It is also one of the most highly conserved proteins, differing by no more than 5% in species as diverse as algae and humans.
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An action potential is a "spike" of electrical discharge that travels along the membrane of a cell. Action potentials are an essential feature of animal life, rapidly carrying information within and between tissues. They also occur in some plants.
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The sliding filament mechanism is a process used by muscles to contract.

Process of Movement

Myosin is a molecular motor that acts like an active ratchet. Chains of actin proteins form high tensile passive 'thin' filaments that transmit the force generated by myosin to the
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Myosins are a large family of motor proteins found in eukaryotic tissues. They are responsible for actin-based motility.

Structure and Function

Domains

Most myosin molecules are composed of both a head and a tail domain.
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Adenosine 5'-triphosphate (ATP) is a multifunctional nucleotide that is most important as a "molecular currency" of intracellular energy transfer. In this role, ATP transports chemical energy within cells for metabolism.
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Adenosine diphosphate, abbreviated ADP, is a nucleotide. It is an ester of pyrophosphoric acid with the nucleotide adenine. ADP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine.
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Phosphocreatine, also known as creatine phosphate or Pcr, is a phosphorylated creatine molecule that is an important energy store in skeletal muscle. It is used to anaerobically generate ATP from ADP, forming creatine for the 2 to 7 seconds following an intense
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Calcium (IPA: /ˈkalsiəm/) is the chemical element in the periodic table that has the symbol Ca and atomic number 20. It has an atomic mass of 40.078.
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A sarcomere is the basic unit of a muscle's cross-striated myofibril. Sarcomeres are multi-protein complexes composed of three different filament systems.
  • The thick filament system is composed of myosin protein which is connected from the M-line to the Z-disc by Titin

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Muscle Origin Insertion Artery Nerve Action Antagonist
occipitofrontalis 2 occipital bellies and 2 frontal bellies. galea aponeurotica facial nerve raises the eyebrows
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muscle is a powerful superficial muscle that is in the back part of the lower leg (the calf). It runs from its 2 heads just above the knee to the heel, and is involved in standing and walking. Along with the soleus muscle it forms the calf muscle.
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The femur or thigh bone is the longest, most voluminous, and strongest bone of mammalian bodies. It forms part of the hip and part of the knee.

The word femur is Latin for thigh.
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calcaneus forms part of the tarsi and constitutes the heel of the human foot or the point of an animal's hock . It is also known as the heel bone.

Human

It articulates with two other tarsal bones, the talus above and the cuboid toward the midfoot.
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The sural arteries (inferior muscular arteries) are two large branches, which are distributed to the Gastrocnemius, Soleus, and Plantaris.

They arise from the popliteal artery opposite the knee-joint.
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The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus.

In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris, and the sural nerve.
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Plantarflexion is the movement which increases the angle between the foot and the leg, as when depressing an automobile pedal. The word "Plantar" translates as "toward the sole" ("Planta").

The movement in the opposite direction is Dorsiflexion.
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flexion is a position that is made possible by the joint angle decreasing. The skeletal (bones, cartilage, and ligaments) and muscular (muscles and tendons) systems work together to move the joint into a "flexed" position.
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In human anatomy, the knee is the lower extremity joint connecting the femur and the tibia. Since in humans the knee supports nearly the entire weight of the body, it is the joint most vulnerable both to acute injury and to the development of osteoarthritis.
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In human anatomy, the tibialis anterior is a muscle in the shin that spans the length of the tibia. It originates in the upper two-thirds of the lateral surface of the tibia and inserts into the medial cuneiform and first metatarsal bones of the foot.
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