Information about Methemoglobin Reductase

Red blood cells are the most common type of blood cell and the vertebrate body's principal means of delivering oxygen from the lungs or gills to body tissues via the blood.
..... Click the link for more information.

In biochemistry, flavin adenine dinucleotide (FAD) is the precursor molecule to FADH₂. Upon bonding to two hydrogen atoms, FAD is then changed to FADH₂ and is turned into an energy-carrying molecule.
..... Click the link for more information.

Protein Data Bank (PDB) is a repository for 3-D structural data of proteins and nucleic acids. This data, typically obtained by X-ray crystallography or NMR spectroscopy, is submitted by biologists and biochemists from around the world, is released into the public domain,
..... Click the link for more information.

The Entrez Global Query Cross-Database Search System is a powerful federated search engine, or web portal that allows users to search many discrete health sciences databases at the National Center for Biotechnology Information (NCBI) website.
..... Click the link for more information.

Hugo is a male given name, a latinized form of the name Hugh, a German/Teutonic name meaning "Bright in Mind and Spirit".

Hugo is one of the most popular names in Europe ranking as high as #2 in France, #6 in Spain, and #7 in Belgium in 2006.
..... Click the link for more information.

Protein Data Bank (PDB) is a repository for 3-D structural data of proteins and nucleic acids. This data, typically obtained by X-ray crystallography or NMR spectroscopy, is submitted by biologists and biochemists from around the world, is released into the public domain,
..... Click the link for more information.

The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland and was founded in 1988.
..... Click the link for more information.

Swiss-Prot is a manually curated biological database of protein sequences. Swiss-Prot was created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute.
..... Click the link for more information.

Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. As a system of enzyme nomenclature, every EC number is associated with a recommended name for the respective enzyme.
..... Click the link for more information.

locus (plural loci) is a fixed position on a chromosome, such as the position of a gene or a biomarker (genetic marker). A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map.
..... Click the link for more information.

Enzymes are proteins that catalyze (i.e. accelerate) chemical reactions.^[1] In enzymatic reactions, the molecules at the beginning of the process are called substrates, and the enzyme converts them into different molecules, the products.
..... Click the link for more information.

Methemoglobin (pronounced MET-hemoglobin) is a form of the oxygen-carrying protein hemoglobin (British English: haemoglobin), in which the iron in the heme group is in the Fe³⁺ state, not the Fe²⁺ of normal hemoglobin. Methemoglobin is unable to carry oxygen.
..... Click the link for more information.

Hemoglobin, also spelled haemoglobin and abbreviated Hb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of the blood in vertebrates and other animals.
..... Click the link for more information.

Methemoglobinemia
Classification & external resources

ICD-10 D 74.
ICD-9 289.7

DiseasesDB 8100

eMedicine med/1466   emerg/313
MeSH D008708

Methemoglobinemia
..... Click the link for more information.

A reductase is an enzyme which lowers the activation energy for a reduction reaction. ^[1][2]

Examples

• 5-alpha reductase
• Dihydrofolate reductase
• HMG-CoA reductase
• Methemoglobin reductase
• Ribonucleotide reductase

..... Click the link for more information.

Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed
..... Click the link for more information.

Nicotinamide adenine dinucleotide (NAD⁺ or in older notation DPN⁺) is an important coenzyme found in cells. It plays key roles as a carrier of electrons and a participant in metabolic redox reactions, as well as in cell signaling.
..... Click the link for more information.

Nicotinamide adenine dinucleotide phosphate (NADP) is used in anabolic reactions, such as fatty acid and nucleic acid synthesis, which require NADPH as a reducing agent.

NADPH is the reduced form of NADP⁺, and NADP⁺ is the oxidized form of NADPH.
..... Click the link for more information.

In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the reductant, also called the hydrogen acceptor or electron donor) to another (the oxidant, also called the hydrogen donor or electron acceptor).
..... Click the link for more information.

Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. As a system of enzyme nomenclature, every EC number is associated with a recommended name for the respective enzyme.
..... Click the link for more information.

The NADPH oxidase (nicotinamide adenine dinucleotide phosphate-oxidase) complex is an enzyme complex

Subunits

It is made up of six subunits. These subunits are:

..... Click the link for more information.

P91-PHOX is a glycoprotein associated with chronic granulomatous disease.

External link

• MeSH gp91phox+protein,+human

..... Click the link for more information.

NADH dehydrogenase (EC 1.6.5.3 ) is an enzyme located in the inner mitochodrial membrane that catalyzes the transfer of electrons from NADH to coenzyme Q (CoQ). It is also called the NADH:quinone oxidoreductase.
..... Click the link for more information.

Proteins are large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid residues.
..... Click the link for more information.

Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin: the flavin adenine dinucleotide (FAD) or flavin mononucleotide (FMN).

Flavoproteins are involved in a wide array of biological processes, including, but by no means limited to, bioluminescence,
..... Click the link for more information.

The acetolactate synthase (ALS) enzyme (also known as acetohydroxyacid synthase, or AHAS) is the first step in the synthesis of the branched-chain amino acids (valine, leucine, and isoleucine).
..... Click the link for more information.

Acyl CoA dehydrogenase is the enzyme used to catalyze the first step of β-oxidation in Fatty acid metabolism.

Reaction

The following reaction is the oxidation of the fatty acid by FAD.

The enzyme catalyzes the formation of a double bond between the C-2 and C-3.
..... Click the link for more information.

Apoptosis inducing factor is a flavoprotein.

See also

• Apoptosis

External links

• MeSH Apoptosis+inducing+factor

..... Click the link for more information.

Butyryl CoA dehydrogenase is a flavoprotein.

It acts upon butyryl-coenzyme A.

See also

• Butyric_acid#Butyrate_fermentation
• Causes_of_hypoglycemia#Metabolic_Defects

External links

• MeSH Butyryl-CoA+Dehydrogenase

..... Click the link for more information.

Identifiers
Symbol CRY2

Entrez 1408
HUGO 2385
OMIM 603732

RefSeq NM_021117
UniProt Q49AN0
Other data

Locus Chr. 11 p11.2 Cryptochrome is a name used historically for the blue light photoreceptors of plants.
..... Click the link for more information.