Information about Hypervariable Control Region
A hypervariable region (HVR) is a location within nuclear DNA or the D-loop of mitochondrial DNA in which base pairs of nucleotides repeat. Repeats in the hypervariable region are highly polymorphic.
HVR1 locations are numbered 16001-16568. HVR2 locations are numbered 001-574.
Genetic genealogy
There are two hypervariable regions used in human mitochondrial genealogical DNA testing. HVR1 is considered a "low resolution" region and HVR2 is considered a "high resolution" region. Getting HVR1 and HVR2 DNA tests can help determine one's haplogroup.HVR1 locations are numbered 16001-16568. HVR2 locations are numbered 001-574.
See also
External links
Nuclear DNA , nuclear deoxyribonucleic acid (nDNA), is DNA contained within a nucleus of eukaryotic organisms. In most cases it encodes more of the genome than the mitochondrial DNA and is passed sexually rather than matrilineally.
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In molecular biology, two nucleotides on opposite complementary DNA or RNA strands that are connected via hydrogen bonds are called a base pair (often abbreviated bp).
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A nucleotide is a chemical compound that consists of 3 portions: a heterocyclic base, a sugar, and one or more phosphate groups. In the most common nucleotides the base is a derivative of purine or pyrimidine, and the sugar is the pentose (five-carbon sugar) deoxyribose or ribose.
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Polymorphism in biology occurs when two or more clearly different types exist in the same population of the same species— in other words, the occurrence of more than one form or morph. The caste system in ants is an example.
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A genealogical DNA test examines the nucleotides at specific locations on a person's DNA for genetic genealogy purposes. The test results are meant to have no informative medical value and do not determine specific genetic diseases or disorders (see possible exceptions in
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human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. These haplogroups have led some researchers to trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread across the globe.
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human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. These haplogroups have led some researchers to trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread across the globe.
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A genealogical DNA test examines the nucleotides at specific locations on a person's DNA for genetic genealogy purposes. The test results are meant to have no informative medical value and do not determine specific genetic diseases or disorders (see possible exceptions in
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The Cambridge Reference Sequence (CRS) for human mitochondrial DNA was first published in 1981 as a forerunner of the human genome project. It should be noted that sometimes the abbreviation "CRS" is used to mean "coding region sequence" with regard to mitochondrial DNA.
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Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed
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