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Information about Glycerol 3 Phosphate

Glycerol 3-phosphate
IUPAC name1,2,3-Propanetriol, 1- (dihydrogen phosphate)
Other names
Glycerol-1-phosphate
Glycerophosphate
Identifiers
CAS number57-03-4
PubChem754
MeSHglycerol+3-phosphate
SMILESOCC(O)COP(O)(O)=O
Properties
Molecular formulaC3H9O6P
Molar mass172.074
Except where noted otherwise, data are given for
materials in their standard state
(at 25 C, 100 kPa)


Glycerol 3-phosphate is a chemical intermediate in the glycolysis metabolic pathway. (It should not be confused with the similarly named glycerate 3-phosphate or glyceraldehyde 3-phosphate.)

Function

Dehydrogenation of L-glycerol 3-phosphate produces DHAP and is part of the entry of glycerol (sourced from triglycerides) into the glycolytic pathway.

The glycerol 3-phosphate shuttle is used to rapidly regenerate NAD+ in the brain and skeletal muscle of mammals.

See also

IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. It is developed and kept up to date under the auspices of the International Union of Pure and Applied Chemistry (IUPAC).
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CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. They are also referred to as CAS numbers, CAS RNs or CAS #s.
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PubChem is a database of chemical molecules. The system is maintained by the National Center for Biotechnology Information (NCBI), a component of the National Library of Medicine, which is part of the United States National Institutes of Health (NIH).
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Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed
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smiles

File extension: .smi
Type of format: chemical file format

The simplified molecular input line entry specification or SMILES
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A chemical formula is a concise way of expressing information about the atoms that constitute a particular chemical compound. A chemical formula is also a short way of showing how a chemical reaction occurs.
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Molar mass, symbol M,[1] is the mass of one mole of a substance (chemical element or chemical compound).[2] It is a physical property which is characteristic of each pure substance.
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standard state of a material is its state at 1 bar (100 kilopascals exactly). This pressure was changed from 1 atm (101.325 kilopascals) by IUPAC in 1990.[1] The standard state of a material can be defined at any given temperature, most commonly 25 degrees Celsius,
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Embden-Meyerhof pathway, initially explained by Gustav Embden and Otto Meyerhof. The term can be taken to include alternative pathways, such as the Entner-Doudoroff Pathway. However, glycolysis will be used here as a synonym for the Embden-Meyerhof pathway.
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Glycerate 3-phosphate (GP) or 3-phosphoglycerate (3PG) is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle.
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Glyceraldehyde 3-phosphate, also known as triose phosphate or 3-phosphoglyceraldehyde and abbreviated as G3P, GADP, GAP or PGAL, is a chemical compound that occurs as an intermediate in several central metabolic pathways of all organisms.
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Dehydrogenation is a chemical reaction that involves the elimination of hydrogen (H2). It is the reverse process of hydrogenation. Dehydrogenation reactions may be either large scale industrial processes or smaller scale laboratory procedures.
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Triglyceride   (help info ) (more properly known as triacylglycerol   (help info ) or triacylglyceride
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The glycerol-3-phosphate shuttle is a mechanism that regenerates NAD+ from NADH, a by-product of glycolysis.

Reaction

In this shuttle, the enzyme called cytoplasmic glycerol-3-phosphate dehydrogenase converts dihydroxyacetone phosphate to glycerol 3-phosphate by oxidizing
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NAD can refer to:
  • Nicotinamide adenine dinucleotide, a coenzyme used in glycolysis
  • National Appeals Division, an agency within the United States Department of Agriculture
  • National Association of the Deaf, a non-profit advocacy organization

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Identifiers
Symbol GPD2

Entrez 2820
HUGO 4456
OMIM 138430

RefSeq NM_000408
UniProt P43304
Other data
EC number 1.1.1.8
Locus Chr. 2 q24.
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