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Information about Cephalon

Cephalon, Inc.
Public (NASDAQ: CEPH)
Founded1987
HeadquartersFrazer, Pennsylvania, United States
Key peopleFrank Baldino, Jr., Chairman and Chief Executive
IndustryBiotechnology
ProductsCentral nervous system, oncology
Employees3,000
Website[1]


Cephalon, Inc. (NASDAQ: CEPH) is a U.S. biopharmaceutical company co-founded in 1987 by Dr. Frank Baldino, Jr., a pharmacologist and former scientist with the DuPont Company, who continues to serve as its chairman and chief executive officer. The company's name relates to the Greek root word "cephalic" meaning "related to the head or brain," and it was established primarily to pursue treatments for neurodegenerative diseases.

Cephalon is a component of the S&P MidCap 400 stock index, and is included in the Fortune 1000 list of U.S. companies based upon annual revenues for 2006.

The company's early research efforts were focused on the development of IGF-1, an insulin-like growth factor, under a collaboration with Chiron Corporation to treat amyotrophic lateral sclerosis, or Lou Gehrig's Disease, but the product has never been approved. More recently, the company has developed and commercialized products for the treatment of sleep disorders, pain, addiction and cancer. In addition to conducting research on kinase inhibitors and other small molecules, it has licensed compounds and acquired both products and other companies, including CIMA Labs, Anesta Corp. and Laboratoire Lafon. Its leading product is PROVIGIL® (modafinil) for the treatment of excessive daytime sleepiness associated with narcolepsy, sleep apnea and shift work sleep disorder. The company also markets ACTIQ® (oral transmucosal fentanyl citrate) and FENTORA® (fentanyl buccal tablet) for cancer pain, GABITRIL® (tiagabine HCl) for seizures, TRISENOX® (arsenic trioxide) for a rare form of leukemia, and VIVITROL® (naltrexone for extended release injectable suspension) for the treatment of alcohol addiction. In 2005, Cephalon bought Europe-based pharmaceutical company Zeneus. This added to its European presence and gave it further products for its portfolio, including ABLECET® (antifungal), TARGRETIN® (bexarotene)for cutaneous T-cell lymphoma and MYOCET® (liposomal doxorubicin) for metastatic breast cancer.

The company has its corporate headquarters west of Philadelphia in Frazer, Pennsylvania and its research operations in nearby West Chester, as well as manufacturing and other operations in suburban Minneapolis, Minnesota and Salt Lake City, Utah; its European operations are based near Paris, France. Sales revenues exceeded one billion dollars in 2005, ranking Cephalon among the ten leading biopharmaceutical companies in the world. In 2006, industry publication MedAd News named the company one of the ten most respected biotechnology firms in the world.

Key executives include J. Kevin Buchi, Dr. Peter Grebow, John E. Osborn, Robert P. Roche and Dr. Jeffry Vaught. Members of the board include venture capitalist William Egan, former COR Therapeutics CEO Vaughan Kailian, health-care economist Dr. Gail Wilensky, former Harvard physician and Glaxo USA head Dr. Charles Sanders and former Ambassador Kevin Moley.

External links

A public company usually refers to a company that is permitted to offer its securities (stock, bonds, etc.) for sale to the general public, typically through a stock exchange.
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The NASDAQ (acronym for National Association of Securities Dealers Automated Quotations system) is an American stock market.
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Frazer is the name of two places in the United States:
  • Frazer in Montana,
  • Frazer Township in Pennsylvania.
Frazer is a marque of American automobile.
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Commonwealth of Pennsylvania

Flag of Pennsylvania Seal
Nickname(s): Keystone State, Quaker State,
Coal State, Oil State
Motto(s): Virtue, Liberty and Independence

Capital Harrisburg
Largest city
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Motto
"In God We Trust"   (since 1956)
"E Pluribus Unum"   ("From Many, One"; Latin, traditional)
Anthem
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Industry (from Latin industrius, "diligent, industrious"), is the segment of economy concerned with production of goods. Industry began in its present form during the 1800s, aided by technological advances, and it has continued to develop to this day.
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Biotechnology is technology based on biology, especially when used in agriculture, food science, and medicine. The United Nations Convention on Biological Diversity has come up with one of many definitions of biotechnology:[1]

"

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Aspinwall Classification System (Leo Aspinwall, 1958) classifies and rates products based on five variables:
  1. Replacement rate (How frequently is the product repurchased?)
  2. Gross margin (How much profit is obtained from each product?)

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The central nervous system (CNS) represents the largest part of the nervous system, including the brain and the spinal cord. Together with the peripheral nervous system, it has a fundamental role in the control of behavior.
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Oncology is the branch of medicine that studies tumors (cancer) and seeks to understand their development, diagnosis, treatment, and prevention. A Medical professional who practices oncology is an oncologist.
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Employment is a contract between two parties, one being the employer and the other being the employee. An employee may be defined as: "A person in the service of another under any contract of hire, express or implied, oral or written, where the employer has
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A website (alternatively, Web site or web site) is a collection of Web pages, images, videos or other digital assets that is hosted on one or several Web server(s), usually accessible via the Internet, cell phone or a LAN.
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The NASDAQ (acronym for National Association of Securities Dealers Automated Quotations system) is an American stock market.
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Motto
"In God We Trust"   (since 1956)
"E Pluribus Unum"   ("From Many, One"; Latin, traditional)
Anthem
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Dupont, DuPont, Du Pont, or du Pont may refer to:

Companies

  • E.I. du Pont de Nemours and Company (DuPont), the world's fourth largest chemical company
  • Du Pont Motors

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Neurodegenerative disease (Greek νέυρο-, néuro-, "nerval" and Latin dēgenerāre, "to decline" or "to worsen") is a condition in which cells of the brain and spinal cord are lost.
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The insulin-like growth factors (IGFs) are polypeptides with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate with their physiologic environment.
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Chiron Corporation

Subsidiary
Founded 1981
Headquarters Emeryville, California, USA

Key people Howard Pien, CEO
Industry Biotechnology
Products Biopharmaceuticals, vaccines, blood testing
Revenue $1.
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Amyotrophic lateral sclerosis
Classification & external resources

ICD-10 G 12.2
ICD-9 335.20

OMIM 105400
DiseasesDB 29148
MedlinePlus 000688
eMedicine neuro/14   emerg/24 pmr/10
MeSH D000690 Amyotrophic lateral sclerosis
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A protein kinase inhibitor is a type of enzyme inhibitor which specifically blocks the action of protein kinase.

Kinase inhibitors such as dasatinib are sometimes used in the treatment of cancer.
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Narcolepsy
Classification & external resources

ICD-10 G 47.4
ICD-9 347

OMIM 161400
DiseasesDB 8801

eMedicine neuro/522  
MeSH D009290

Narcolepsy
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MeSH D012891

Sleep apnea, sleep apnoea or sleep apnœa is a sleep disorder characterized by pauses in breathing during sleep. These episodes, called apneas (literally, "without breath"), each last long enough so one or more breaths are missed, and
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Shift work sleep disorder is a circadian rhythm sleep disorder which affects people who change their work or sleep schedules frequently. Such recurrent interruption of sleep patterns may result in insomnia and/or excessive sleepiness.
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Flag
Seal
Nickname: "City of Brotherly Love", "The City that Loves you Back", "Cradle of Liberty", "The Quaker City", "The Birthplace of America", "Philly".
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Frazer, Pennsylvania may mean:

Places

  • A community in East Whiteland Township, Pennsylvania
  • Frazer Township, Pennsylvania

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West Chester is the name of some places in the United States of America:
  • West Chester Township, Butler County, Ohio
  • West Chester, Ohio
  • West Chester, Pennsylvania
West Chester is also the name for a university in Pennsylvania

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Minneapolis, Minnesota
Downtown seen from the North Loop

Flag
Seal
Nickname: City of Lakes, Mill City
Motto: En Avant (French: 'Forward')
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Salt Lake City, Utah
Downtown Salt Lake City
Nickname: Crossroads of the West, SLC
Location of Salt Lake City in Salt Lake County, Utah
Coordinates:
Country United States
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Ville de Paris

City flag City coat of arms

Motto: Fluctuat nec mergitur
(Latin: "Tossed by the waves, she does not sink")

The Eiffel Tower in Paris, as seen from the esplanade du Trocadéro.
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Motto
Liberté, Égalité, Fraternité
"Liberty, Equality, Fraternity"
Anthem
"La Marseillaise"


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