Information about Blood Flow

Blood flow is the flow of blood in the cardiovascular system. The discovery that blood flows is attributed to William Harvey.

Mathematically, blood flow is described by Darcy's law (which can be viewed as the fluid equivalent of Ohm's law) and approximately by Hagen-Poiseuille's law. Blood is an inhomogeneous medium consisting mainly of plasma and a suspension of red blood cells. White cells, or leukocytes, and platelets while present in smaller concentrations, play an important role in biochemical processes, such as immune response, inflammation, and coagulation. Red cells tend to coagulate when the flow shear rates are low, while increasing shear rates break these formations apart, thus reducing blood viscosity.This results in two non-Newtonian blood properties, shear thinning and yield stress. In healthy large arteries blood can be successfully approximated as a homogeneous, Newtonian fluid since the vessel size is much greater than the size of particles and shear rates are sufficiently high that particle interactions may have a negligible effect on the flow. In smaller vessels, however, non-Newtonian blood behavior should be taken into account. The flow in healthy vessels is generally laminar, however in diseased (e.g. atherosclerotic) arteries the flow may be transitional or turbulent. The first equation below is Darcy's law, the second is the Hagen-Poiseuille law:





where:

F = blood flow
P = pressure
R = resistance
ν = fluid viscosity


L = length of tube
r = radius of tube


In the last equation it is important to note that resistance to flow changes dramatically with respect to the radius of the tube. This is important in angioplasty, as it enables the increase of blood flow with balloon catheter to the deprived organ significantly with only a small increase in radius of a vessel.

See also

Blood is a specialized biological fluid consisting of red blood cells (also called RBCs or erythrocytes), white blood cells (also called leukocytes) and platelets (also called thrombocytes) suspended in a complex fluid medium known as blood plasma.
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Circulatory System is a psychedelic rock musical ensemble formed by musician/painter Will Cullen Hart, and featuring Hannah Jones, Derek Almstead, Peter Erchick, John Fernandes, and Heather McIntosh.
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William Harvey (April 1, 1578 – June 3, 1657) was an English medical doctor, who is credited with being the first to correctly describe, in exact detail, the properties of blood being pumped around the body by the heart.
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Mathematics (colloquially, maths or math) is the body of knowledge centered on such concepts as quantity, structure, space, and change, and also the academic discipline that studies them. Benjamin Peirce called it "the science that draws necessary conclusions".
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In fluid dynamics, Darcy's law is a phenomologically derived constitutive equation that describes the flow of a fluid through a porous medium. The law was formulated by Henry Darcy based on the results of experiments[1] on the flow of water through beds of sand.
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Ohm's law states that, in an electrical circuit, the current passing through a conductor between two points is proportional to the potential difference (i.e. voltage drop or voltage) across the two points, and inversely proportional to the resistance between them.
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Poiseuille's law is the physical law concerning the voluminal laminar stationary flow Φ of an incompressible uniform viscous liquid (so called Newtonian fluid) through a cylindrical tube with constant circular cross-section.
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Intervention:


ICD-10 code:
ICD-9 code: 00.6

Other codes: Angioplasty is the mechanical widening of a narrowed or totally-obstructed blood vessel. These obstructions are often caused by atherosclerosis.
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A balloon catheter is a type of "soft" catheter with an inflatable "balloon" at its tip which is used during a catheterization procedure to enlarge a narrow opening or passage within the body.
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Heart rate is a term used to describe the frequency of the cardiac cycle. It is considered one of the four vital signs. Usually it is calculated as the number of contractions (heart beats) of the heart in one minute and expressed as "beats per minute" (bpm).
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