Information about Alamethicin
Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. It contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. The peptide sequence is:
Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phl
(Ac = acetyl, Phl = phenylalaninol)
data copied from Fermentek Alamethicin product page
2-Aminoisobutyric acid, or α-aminoisobutyric acid (AIB) or α-methylalanine or 2-methylalanine, is an amino acid with the structural formula is H2N-C(CH3)
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Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phl
(Ac = acetyl, Phl = phenylalaninol)
- Molecular Formula: C92H150N22O25
- CAS number: 27061-78-5
- Appearance: Off white solid
- UV spectrum maxima: 265, 257
- Melting point: 255°C-270°C
- Solubility information: DMSO, Methanol, Ethanol. Not soluble in water
data copied from Fermentek Alamethicin product page
Peptides (from the Greek πεπτίδια, "small digestibles") are short polymers formed from the linking, in a defined order, of α-amino acids.
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antibiotic is a chemotherapeutic agent that inhibits or abolishes the growth of micro-organisms, such as bacteria, fungi, or protozoans. The term originally referred to any agent with biological activity against living organisms; however, "antibiotic" now is used to refer to
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T. viride
Binomial name
Trichoderma viride
Pers., (1794)
Synonyms
Hypocrea contorta (Schwein.) Berk. & M.A. Curtis, (1875)
Hypocrea rufa (Pers.) Fr., Summa veg. Scand.
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Binomial name
Trichoderma viride
Pers., (1794)
Synonyms
Hypocrea contorta (Schwein.) Berk. & M.A. Curtis, (1875)
Hypocrea rufa (Pers.) Fr., Summa veg. Scand.
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Proteinogenic amino acids, also known as standard, normal, or primary amino acids, are those 20 amino acids that are found in proteins and that are coded for in the standard genetic code. Proteinogenic literally means protein building.
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amino acid is a molecule that contains both amine and carboxyl functional groups. In biochemistry, this term refers to alpha-amino acids with the general formula H2NCHRCOOH, where R is an organic substituent.
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For other uses, see AIB.
2-Aminoisobutyric acid, or α-aminoisobutyric acid (AIB) or α-methylalanine or 2-methylalanine, is an amino acid with the structural formula is H2N-C(CH3)
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A helix (pl: helices), from the Greek word έλικας/έλιξ
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A helix (pl: helices), from the Greek word έλικας/έλιξ
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CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. They are also referred to as CAS numbers, CAS RNs or CAS #s.
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Voltage (sometimes also called electric potential difference or electrical tension) is the potential similarity of electrical potential between two points of an electrical or electronic circuit, expressed in volts.
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ion is an atom or molecule which has lost or gained one or more electrons, making it positively or negatively charged. A negatively charged ion, which has more electrons in its electron shells than it has protons in its nuclei, is known as an anion
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molecule is defined as a sufficiently stable electrically neutral group of at least two atoms in a definite arrangement held together by strong chemical bonds.[1][2] In organic chemistry and biochemistry, the term molecule
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Fermentek Biotechnology Ltd.
Private
Founded 1995
Headquarters Israel
Key people Dr Yosef Behrend , President and CEO
Industry Biotechnology
Products Special bioactive compounds for research
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Private
Founded 1995
Headquarters Israel
Key people Dr Yosef Behrend , President and CEO
Industry Biotechnology
Products Special bioactive compounds for research
..... Click the link for more information.
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