Information about Airway Resistance

Airway resistance is a concept used in respiratory physiology to describe mechanical factors which limit the access of inspired air to the pulmonary alveoli, and thus determine airflow.

Resistance is greatest at the bronchi of intermediate size, in between the fourth and eighth bifurcation.[1]

Because airway resistance is dictated by the diameter of the airways and by the density of the inspired gas, the low density of heliox reduces airway resistance, and makes it easier to ventilage the lungs.

Resistance can be calculated using Ohm's law[2] or Poiseuille's law.[3]

Ohm's law

  • R = resistance
  • P = pressure
  • V* = airflow (the asterisk should be read as a dot over the letter, which is used to denote rate in respiratory physiology.)

Poiseuille's law



(rewrite)
  • R = resistance
  • n = viscosity
  • l = length
  • r = radius
Because of the fourth power in the denominator, resistance increases rapidly as diameter decreases.

See also

References

External links

Respiratory physiology is the branch of human physiology focusing upon respiration.

Topics include:

Volumes

  • lung volumes
  • vital capacity
  • functional residual capacity
  • dead space
  • spirometry
  • body plethysmography
  • peak flow meter


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alveolus (plural: alveoli, from Latin alveus, "little cavity"), is an anatomical structure that has the form of a hollow cavity. Mainly found in the lung, the pulmonary alveoli
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A bronchus (plural bronchi, adjective bronchial) is a caliber of airway in the respiratory tract that conducts air into the lungs. No gas exchange takes place in this part of the lungs.
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See Heliox (cryogenic equipment) for another use of the word Heliox


Heliox is a breathing gas that is composed of a mixture of helium (He) and oxygen (O2).
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lungs flank the heart and great vessels in the chest cavity.[1]]]

The lung is the essential respiration organ in air-breathing vertebrates, the most primitive being the lungfish.
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Ohm's law states that, in an electrical circuit, the current passing through a conductor between two points is proportional to the potential difference (i.e. voltage drop or voltage) across the two points, and inversely proportional to the resistance between them.
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Poiseuille's law is the physical law concerning the voluminal laminar stationary flow Φ of an incompressible uniform viscous liquid (so called Newtonian fluid) through a cylindrical tube with constant circular cross-section.
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A rate is a special kind of ratio, indicating a relationship between two measurements with different units, such as miles to gallons or cents to pounds.

Example

When dealing with rates, the division operator is sometimes expressed as per.
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Respiratory physiology is the branch of human physiology focusing upon respiration.

Topics include:

Volumes

  • lung volumes
  • vital capacity
  • functional residual capacity
  • dead space
  • spirometry
  • body plethysmography
  • peak flow meter


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turbulence or turbulent flow is a flow regime characterized by chaotic, stochastic property changes. This includes low momentum diffusion, high momentum convection, and rapid variation of pressure and velocity in space and time.
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Laminar flow, sometimes known as streamline flow, occurs when a fluid flows in parallel layers, with no disruption between the layers. In fluid dynamics, laminar flow is a flow regime characterized by high momentum diffusion, low momentum convection, pressure and velocity
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In fluid mechanics, the Reynolds number is the ratio of inertial forces (vsρ) to viscous forces (μ/L) and consequently it quantifies the relative importance of these two types of forces for given flow conditions.
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Upper Airway Resistance Syndrome or UARS is a sleep condition characterized by airway resistance to breathing during sleep. The primary symptoms include daytime sleepiness and excessive fatigue.
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Medical College of Georgia is the smallest of four research schools in the University System of Georgia (USG). MCG currently has 5 undergraduate and graduate schools on campus: The School of Medicine, School of Dentistry, School of Nursing, School of Allied Health, and Graduate
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Medical College of Georgia is the smallest of four research schools in the University System of Georgia (USG). MCG currently has 5 undergraduate and graduate schools on campus: The School of Medicine, School of Dentistry, School of Nursing, School of Allied Health, and Graduate
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Medical College of Georgia is the smallest of four research schools in the University System of Georgia (USG). MCG currently has 5 undergraduate and graduate schools on campus: The School of Medicine, School of Dentistry, School of Nursing, School of Allied Health, and Graduate
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respiratory system generally includes tubes, such as the bronchi, used to carry air to the lungs, where gas exchange takes place. A diaphragm pulls air in and pushes it out. Respiratory systems of various types are found in a wide variety of organisms.
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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems.
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Respiratory physiology is the branch of human physiology focusing upon respiration.

Topics include:

Volumes

  • lung volumes
  • vital capacity
  • functional residual capacity
  • dead space
  • spirometry
  • body plethysmography
  • peak flow meter


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Larger volumes Smaller volumes
males females
taller people shorter people
non-smokers heavy smokers
professional athletes[1] non-athletes
people living at high altitudes people living at low altitudes
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Vital capacity is the maximum volume of air that a person can exhale after maximum inhalation. It can also be the maximum volume of air that a person can inhale after maximum exhalation.
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Functional Residual Capacity (FRC) is the volume of air present in the lungs at the end of passive expiration. At FRC, the elastic recoil forces of the lungs and chest wall are equal but opposite and there is no exertion by the diaphragm or other respiratory muscles.
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Respiratory minute volume (or minute ventilation, or flow of gas) is the volume of air which can be inhaled (inhaled minute volume) or exhaled (exhaled minute volume) from a person's lungs in one minute.
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dead space is air that is inhaled by the body in breathing, but does not partake in gas exchange.

In adults, it is usually in the range of 150ml.[1]

Understanding dead space


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Spirometry (meaning the measuring of breath) is the most common of the Pulmonary Function Tests (PFTs), measuring lung function, specifically the measurement of the amount (volume) and/or speed (flow) of air that can be inhaled and exhaled.
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A peak flow meter is a small, hand-held device used to manage asthma by monitoring airflow through the bronchi and thus the degree of restriction in the airways. The peak flow meter measures the patient's maximum ability to expel air from the lungs, or
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ventilation (or ventilation rate) is the rate at which gas enters or leaves the lung. It is categorised under the following definitions:

Measurement Equation Description
Minute ventilation = tidal volume * respiratory rate[1]
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Positive pressure ventilators help patients with respiratory problems to breathe easier. They use high pressure gas at the opening of the patients lungs in order to mobilize oxygen flow down the pressure gradient, and into the patient's lungs.
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Breathing transports oxygen into the body and carbon dioxide out of the body. Aerobic organisms require oxygen to create energy via respiration, in the form of energy-rich molecules such as glucose. The medical term for normal relaxed breathing is eupnoea.
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