Information about Upregulation
Upregulation is the process by which a cell increases the number of a cellular components, such as RNA or protein in response to external variable. A decrease of component is called downregulation.
For example, the cell increasing the number of receptors to a given hormone or neurotransmitter to improve its sensitivity to this molecule.
In biochemistry, a receptor is a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand), such as a neurotransmitter, hormone, or other substance, and initiates
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For example, the cell increasing the number of receptors to a given hormone or neurotransmitter to improve its sensitivity to this molecule.
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Downregulation is the process by which a cell decreases the number of a cellular component, such as RNA or protein in response to external variable. A increase of component is called upregulation.
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For other uses, see Receptor.
In biochemistry, a receptor is a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand), such as a neurotransmitter, hormone, or other substance, and initiates
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hormone (from Greek όρμή - "to set in motion") is a chemical messenger that carries a signal from one cell (or group of cells) to another. All multicellular organisms produce hormones (including plants - see phytohormone).
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Neurotransmitters are chemicals that are used to relay, amplify and modulate signals between a neuron and another cell. According to the prevailing beliefs of the 1960s, a chemical can be classified as a neurotransmitter if it meets the following conditions:
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Regulation of gene expression (or gene regulation) refers to the cellular control of the amount and timing of changes to the appearance of the functional product of a gene.
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Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed
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