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Information about Sanofi Aventis

Sanofi-Aventis
Public (Euronext SAN, NYSE, LSE and FWB)
FoundedAugust 20, 2004 by acquisition
HeadquartersParis, France
Key peopleJean-François Dehecq Chairman
Gérard Le Fur CEO
IndustryPharmaceutical
ProductsCardiovascular, central nervous system, oncology, and internal medicine formulations.
Flagship products:
Allegra® (allergy)
Lovenox® (deep vein thrombosis)
Plavix® (thrombosis)
Avapro® (hypertension)
Ambien® (insomnia)
Eloxatin® (chemotherapy)
Ketek® (ketolide antibiotic)
Revenue27.311 billion euros (2005)
   ($34.013 billion USD)
Employees96,439 (2004)
Websiteen.sanofi-aventis.com
Sanofi-Aventis (Euronext: SAN, NYSE: SNY), headquartered in Paris, France, is one of the five largest pharmaceutical companies in the world, along with Pfizer, Bristol-Myers Squibb, Novartis, and GlaxoSmithKline. Sanofi-Aventis engages in the research, development, manufacturing and marketing of pharmaceutical products for sale principally in the prescription market, but they also develop over-the-counter medication. Sanofi-Aventis cover 7 major therapeutic areas: cardiovascular, thrombosis, oncology, diabetes, central nervous system, internal medicine and vaccines (with its subsidiary Sanofi-Pasteur).

History

Sanofi aventis

Sanofi aventis was formed in 2004 when Sanofi-Synthélabo acquired Aventis. In early 2004, Sanofi-Synthélabo made a hostile takeover bid worth €47.8 bn against Aventis. Initially, Aventis rejected the bid because it offered inferior value based on the company's share value. The three-month takeover battle concluded when Sanofi-Synthélabo launched a friendly bid of €54.5 bn in place of the previously rejected hostile bid. Government intervention also played an active role. The French government, desiring a local solution, put heavy pressure on Sanofi-Synthélabo to raise its bid for Aventis after it became known that Novartis, a Swiss pharmaceutical company, was in the running.

Sanofi-Synthélabo

Sanofi-Synthélabo was formed in 1999 when Sanofi (former subsidiary of Total) merged with Synthélabo (former subsidiary of L'Oréal). The merged company was based in Paris, France.

Aventis

Main article: Aventis
Aventis was formed in 1999 when Rhône-Poulenc S.A. merged with Hoechst Marion Roussel, which itself was formed from the merger of Hoechst AG with Roussel Uclaf and Marion Merrell Dow. The merged company was based in Schiltigheim, near Strasbourg, France.

Business

Management

Dehecq has been the General Manager of Sanofi since its creation in 1973 until the end of 2006.

Stockholders

Earnings

In 2003, Sanofi-Aventis's consolidated sales was €25 bn. It has operations in more than 100 countries throughout the 5 continents and has 99,700 employees worldwide. Research and development investment was €4 bn.
  • Sales by activity breakdown: 39% from Cardiovascular/Thrombosis, 29% from Central Nervous System, 18% from Internal Medicine, 11% from Oncology, 3% from other pharmaceutical products.
  • Sales by geographic area breakdown: 58% from Europe, 24% from U.S., 18% from rest of the world.

Aventis Foundation

The Aventis Foundation, a German charitable trust, was established in 1996 as the Hoechst Foundation with an endowment of €50 million. In 2000, the foundation was renamed the Aventis Foundation subsequent to the 1999 merger of Hoechst and Rhône-Poulenc. The foundation was responsible for sponsoring the Aventis Prizes for Science Books, which celebrate the very best in popular science writing for adults and children, and which have grown to be one of the world's most prestigious non-fiction literary prizes. In 2006, the foundation severed its connection with the prizes and from 2007 they have been known as the Royal Society Prizes for Science Books and are managed by the Royal Society, the UK national academy of science.

Company profiles

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The central nervous system (CNS) represents the largest part of the nervous system, including the brain and the spinal cord. Together with the peripheral nervous system, it has a fundamental role in the control of behavior.
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Oncology is the branch of medicine that studies tumors (cancer) and seeks to understand their development, diagnosis, treatment, and prevention. A Medical professional who practices oncology is an oncologist.
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Internal medicine is the branch and specialty of medicine concerning the diagnosis and nonsurgical treatment of diseases in adults, especially of internal organs. Doctors of internal medicine
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Fexofenadine hydrochloride (brand names include Allegra and Telfast) is an antihistamine drug used in the treatment of hayfever and similar allergy symptoms. It was developed as a successor of and alternative to terfenadine (brand names include Triludan and
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Enoxaparin is a low molecular weight heparin manufactured by Sanofi-Aventis. It is marketed as Lovenox or Clexane. Enoxaparin injections are derived from the intestinal mucosa of pigs.
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Clopidogrel is a potent oral antiplatelet agent often used in the treatment of coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix.
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Irbesartan (INN) (IPA: [ɜrbəˈsatən]) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. Irbesartan was developed by Sanofi Research (now part of sanofi-aventis).
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Zolpidem is a prescription short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to benzodiazepine receptors which are located on the gamma-aminobutyric acid receptors.
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Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as FOLFOX for the treatment of colorectal cancer.
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Telithromycin is the first ketolide antibiotic to enter clinical use. It is used to treat mild to moderate respiratory infections. Telithromycin is sold under the brand name of Ketek®.

Telithromycin is a semi-synthetic erythromycin derivative.
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Ketolides are antibiotics belonging to the macrolide group. Ketolides are derived from erythromycin by substituting the cladinose sugar with a keto-group and attaching a cyclic carbamate group in the lactone ring.
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