Information about Negri Bodies
Micrograph with numerous rabies virions (small dark-grey rod-like particles) and Negri bodies, larger pathognomonic cellular inclusions of rabies infection.
Description: This micrograph depicts the histopathologic changes associated with rabies encephalitis prepared using an H&E stain. Note the Negri bodies, which are cellular inclusions found most frequently in the pyramidal cells of Ammon's horn, and the Purkinje cells of the cerebellum. They are also found in the cells of the medulla and various other ganglia.
Negri bodies are eosinophilic, sharply outlined, pathognomonic inclusion bodies (2–10 µm in diameter) found in the cytoplasm of certain nerve cells containing the virus of rabies, especially in Ammon's horn of the hippocampus.
External links
- Negri+bodies at eMedicine Dictionary
- synd/2491 at Who Named It
- Slide at pathmicro.med.sc.edu - see bottom
- See pathology video of Negri bodies
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Pathognomonic (often misspelled as pathognomic) is an adjective of Greek origin (παθογνωμονικό [σύμπτωμα]), often used in medicine, which means
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1 micrometre =
SI units
010−6 m 010−3 mm
US customary / Imperial units
010−6 ft 010−6 in
A micrometre (American spelling: micrometer; symbol µmSI units
010−6 m 010−3 mm
US customary / Imperial units
010−6 ft 010−6 in
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Cytoplasm is a gelatinous, semi-transparent fluid that fills most cells. Eukaryotic cells contain a nucleus that is kept separate from the cytoplasm by a double membrane layer. The cytoplasm has three major elements; the cytosol, organelles and inclusions.
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Neurons (also known as neurones and nerve cells) are electrically excitable cells in the nervous system that process and transmit information. In vertebrate animals, neurons are the core components of the brain, spinal cord and peripheral nerves.
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Rabies virus
Rabies
Classification & external resources
ICD-10 A 82. -
ICD-9 071
DiseasesDB 11148
MedlinePlus 001334
eMedicine med/1374 emerg/493 ped/1974
MeSH D011818
Rabies
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Rabies
Classification & external resources
ICD-10 A 82. -
ICD-9 071
DiseasesDB 11148
MedlinePlus 001334
eMedicine med/1374 emerg/493 ped/1974
MeSH D011818
Rabies
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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It forms a part of the limbic system and plays a part in memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.
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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It forms a part of the limbic system and plays a part in memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.
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eMedicine is an online clinical medical knowledge base that was founded in 1996 by Scott Plantz and Richard Lavely, two medical doctors. It was sold to WebMD in January 2006.
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Who Named It? is an English-language dictionary of medical eponyms and the people associated with their identification. Though this is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliographies.
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