Information about Mestranol

In chemistry, a methyl group is a hydrophobic alkyl functional group derived from methane (CH₄). It has the formula -CH₃ and is very often abbreviated as -Me in the structure of a molecule. This hydrocarbon unit can be found in many organic compounds.
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Ether is the general name for a class of chemical compounds which contain an ether group — an oxygen atom connected to two (substituted) alkyl or aryl groups — of general formula R–O–R'.
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Ethinylestradiol, also ethinyl estradiol (EE), is a synthetic derivative of estradiol. Ethinyl estradiol is orally bio-active and the estrogen in almost all modern formulations of combined oral contraceptive pills (the Pill). It is one of the most commonly used medications.
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Estrogens (alternative spellings: oestrogens or œstrogens) are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone.
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Combined Oral Contraceptive Pill (COCP), often referred to as "the Pill", is a combination of an estrogen (oestrogen) and a progestin (progestogen), taken by mouth to inhibit normal fertility.
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A prodrug is a pharmacological substance (drug) which is administered in an inactive (or significantly less active) form. Once administered, the prodrug is metabolised in vivo into the active compound.
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Bioequivalence is a term in pharmacokinetics used to assess the expected in vivo biological equivalence of two proprietary preparations of a drug. If two products are said to be bioequivalent it means that they would be expected to be, for all intents and purposes, the
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Sex steroids, also known as gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. The term sex hormone nearly always is synonymous with sex steroid.
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A section of the Anatomical Therapeutic Chemical Classification System.

G Genito-urinary system and sex hormones

G03A Hormonal contraceptives for systemic use

G03AA Progestogens and estrogens, fixed combinations

G03AA01 Etynodiol and estrogen

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A section of the Anatomical Therapeutic Chemical Classification System.

L Antineoplastic and immunomodulating agents

L02A Hormones and related agents

L02AA Estrogens

L02AA01 Diethylstilbestrol

L02AA02 Polyestradiol phosphate

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Progestagens (also spelled progestogens or gestagens) are hormones that produce effects similar to those of progesterone, the only natural progestagen. All other progestogens are synthetic and are often referred to as progestins.
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The progesterone receptor is an intracellular steroid receptor that specifically binds progesterone. Expressed by a single gene (chromosome 11q22), it has two main forms, A and B, that differ in their molecular weight.
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Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation) and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestogens, and is the major naturally occurring human
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Desogestrel is a molecule used in hormonal contraceptives.

Controversy

In February of 2007, the consumer adovcacy group Public Citizen released a petition requesting that the FDA ban oral contraceptives containing desogestrel, citing studies going as far back as 1995 that
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Drospirenone is a synthetic progestin that is an analog to spironolactone. Its molecular weight is 366.5 and its molecular formula is C₂₄H₃₀O₃.

Properties and uses

The compound is part of certain birth control formulations.
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Dydrogesterone is a progestogen hormone. The brand name is Duphaston and manufactured by Solvay Pharmaceuticals.

Dydrogesterone was first introduced to the market in 1961, and is currently approved in over 100 countries world-wide.
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Ethisterone is a progestogen hormone.

The first orally active progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone), the 17α-ethynyl analog of testosterone, was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur
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Etonogestrel is a molecule used in hormonal contraceptives, most notably the subdermal implant Implanon.

Etonogestrel, the specific progestin used in NuvaRing, is the active metabolite of the inactive prodrug desogestrel, one of two third-generation progestins found in some
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Ethynodiol diacetate is a molecule used in hormonal contraceptives.


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Gestodene is a progestogen used in hormonal contraceptives.

See also

• Progestin

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Gestonorone is a progestagen hormone.


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Levonorgestrel (or -norgestrel or -norgestrel) is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.

Chemistry

Chemically, it is a hormonally active levorotatory enantiomer of the racemic mixture norgestrel.
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Lynestrenol is a progestagen hormone.


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Medroxyprogesterone is a progestin, and is commonly a component of hormonal contraceptives. It can be used in the treatment of endometriosis, abnormal menstrual bleeding or amenorrhea.
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Megestrol is a progesterone derivative with antineoplastic properties used in the treatment of advanced carcinoma of the breast and endometrium. When given in relatively high doses, Megestrol can substantially increase appetite in most individuals, even those with advanced cancer.
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Norelgestromin is a molecule used in hormonal contraceptives. This form of progestin is used in the contraceptive patch, Ortho Evera.

See also

• Progestin
• Contraceptive patch

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Norethisterone (or norethindrone) (or 19-nor-17α-ethynyltestosterone) is a molecule used in some combined oral contraceptive pills and in some progestogen only pills.
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Norethynodrel was the progestin used in Enovid, the first oral contraceptive.


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Norgestimate is a molecule used in hormonal contraceptives.

Norgestimate is a form of progesterone, which is a female hormone important for the regulation of ovulation and menstruation.
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Norgestrel is a progestin used in hormonal contraceptives. Norgestrel is a mixture of two stereoisomers, dextro-norgestrel (CAS# 797-64-8) and levo-norgestrel (CAS# 797-63-7). Only levonorgestrel is biologically active.
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