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Information about Louis Antoine Ranvier

Louis-Antoine Ranvier (b. Lyon, France, October 2, 1835; d. Vendranges, France, March 22, 1922, French physician, pathologist, anatomist and histologist, discoverer of the myelin sheath and the nodes of Ranvier, subcellular structure which covers the axons of neurons.

Ranvier studied medicine at Lyon, graduating in 1865. He founded a small private research laboratory with Victor André Cornil (1837-1908), and together they offered a course in histology to medical students. They also wrote together an important textbook on histopathology. In 1867 he entered the Collège de France and worked as an assistant to Claude Bernard (1813-1878), later, he was appointed to its chair of general anatomy in 1875.

In 1878 he discovered myelin and the famous nodes which received his name. Other anatomical structures which bear his name are the Merkel-Ranvier cells, melanocyte-like cells in the basal layer of the epidermis that contain catecholamine granules; and Ranvier's tactile disks, a special type of sensory nerve ending. In 1897 he founded the scientific journal Archives d'Anatomie Microscopique with Edouard-Gérard Balbiani (1823-1899).

Some of his most noted students were Ferdinand-Jean Darier, Justin Marie Jolly, Joaquín Albarrán, Luis Simarro Lacabra (1851-1921), Fredrik Georg Gade (1855-1933)

He retired in 1900 to his estate in Thélis and died in 1922.

Bibliography

  • Ranvier, Louis-Antoine and Victor André Cornil. 1869. Manuel d'histologie pathologique. Paris
  • Ranvier, Louis-Antoine. 1875-1882. Traité technique d'histologie. Paris
  • Ranvier, Louis-Antoine. 1878. Leçons sur l'histologie du système nerveux, par M. L. Ranvier, recueillies par M. Ed. Weber. Paris
  • Ranvier, Louis-Antoine. 1880. Leçons d'anatomie generale sur le système musculaire, par L. Ranvier, recueillies par M. J. Renaut. Paris
  • Ranvier, Louis-Antoine. 1885. Exposé des titres et des travaux de M. L. Ranvier. Paris

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Ville de Lyon

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Liberté, Égalité, Fraternité
"Liberty, Equality, Fraternity"
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physician applies to a person who practices some type of medicine. Such medical practitioners are concerned with maintaining or restoring human health through the study, diagnosis and treatment of disease and injury, through both an area of knowledge
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Pathologist redirects here. For other uses of the terms pathology or pathological, see pathology (disambiguation).


Pathology is the study and diagnosis of disease through examination of organs, tissues, cells and bodily fluids.
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Myelin is an electrically insulating phospholipid layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
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Nodes of Ranvier, also known as neurofibril nodes, are regularly spaced gaps in the myelin sheath around an axon or nerve fiber. About one micrometer in length, these gaps expose the axonal membrane to the extracellular fluid.
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axon or nerve fiber, is a long, slender projection of a nerve cell, or neuron, that conducts electrical impulses away from the neuron's cell body or soma.

Anatomy


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Neurons (also known as neurones and nerve cells) are electrically excitable cells in the nervous system that process and transmit information. In vertebrate animals, neurons are the core components of the brain, spinal cord and peripheral nerves.
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Victor André Cornil, also André-Victor Cornil (1837-1908) was a French pathologist who was a professor at the University of Paris. He received his doctorate in Paris in 1860, and was later a member of the Académie Nationale de Médecine.
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Histology (from the Greek ἱστός) is the study of tissue sectioned as a thin slice, using a microtome. It can be described as microscopic anatomy.
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Histopathology (from the Greek histos (tissue) and pathos (suffering)) refers to the microscopic examination of tissue in order to study the manifestations of disease.
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Collège de France is a higher education and research establishment (Grand établissement) located in Paris, France, in the 5th arrondissement, or Latin Quarter, across the street from the historical campus of La Sorbonne at the intersection of Rue Saint-Jacques and Rue des
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Claude Bernard (July 12, 1813 – February 10, 1878) was a French physiologist. He was called by I. Bernard Cohen of Harvard University, "one of the greatest of all men of science" in his Foreword to the Dover edition (1957) of Bernard's classic on scientific method,
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Anatomy (from the Greek ἀνατομία anatomia, from ἀνατέμνειν
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Melanocytes are cells located in the bottom layer (the stratum basale) of the skin's epidermis and in the middle layer of the eye (the uvea).

Melanogenesis

Through a process called melanogenesis
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Epidermis is the outermost layer of the skin. It forms the waterproof, protective wrap over the body's surface and is made up of stratified squamous epithelium with an underlying basal lamina.
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Catecholamines are chemical compounds derived from the amino acid tyrosine containing catechol and amine groups. Some of them are biogenic amines. Catecholamines are water soluble and are 50% bound to plasma proteins, so they circulate in the bloodstream.
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Sensory nerves are nerves that receive sensory stimuli, such as how something feels and if it is painful.

They are made up of nerve fibers, called sensory fibers (mechanoreceptor fibers sense body movement and pressure placed against the body, and nociceptor fibers sense
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Edouard-Gérard Balbiani (July 31, 1823 - July 25, 1899 was a French embryologist who was born in Port-au-Prince, Haiti. He was educated in Frankfurt and Paris. In Paris he studied natural sciences under famed zoologist Henri Marie Ducrotay de Blainville (1777-1850).
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Darier Jean Ferdinand (b. April 26 1856, Budapest, Hungary; d. 1938, Paris, France) was a French physician, pathologist and dermatologist.

Darier was a brilliant clinician and outstanding pathologist, who studied with Louis-Antoine Ranvier (1835-1922) at the Collège de
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Justin Marie Jolly (August 6, 1870 Р1953) was a French physician known for his work in haematology. He studied medicine at the Coll̬ge de France under Louis-Antoine Ranvier (1835-1922) and Louis-Charles Malassez (1842-1909) where he learned histological techniques and their
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Joaquín Albarrán, full name Joaquin Albarrán Maria y Dominguez (May 9, 1860 – January 17, 1912) was a French urologist who was born in Sagua La Grande, Cuba. In 1878 he went to Paris, where he worked and studied under many renowned physicians.
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Luis Simarro Lacabra (January 6, 1851 - June 19, 1921) was a Spanish psychiatrist who was born in Rome while his parents were travelling in Italy. He studied medicine in Valencia and Madrid, and in 1877 was appointed director of an insane asylum outside of Madrid.
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