Information about Kussmaul Breathing

Kussmaul breathing is the very deep and labored breathing with normal or reduced frequency,[1] found among people with severe acidosis; it is a form of hyperventilation.[2] Kussmaul breathing is named for Adolph Kussmaul, the 19th century German doctor who first noted it among patients with advanced diabetes (usually type I). He published his finding in a classic 1874 paper.[3]

The cause of Kussmaul breathing is respiratory compensation for a metabolic acidosis, most commonly occurring in diabetics in diabetic ketoacidosis. Blood gases on a patient with Kussmaul breathing will show a low pCO2 because of a forced increased respiration (blowing off the carbon dioxide). The patient feels an urge to breathe deeply, an "air hunger", and it appears almost involuntary.

A metabolic acidosis soon produces hyperventilation, but at first it will tend to be rapid and relatively shallow. Kussmaul breathing develops as the acidosis grows more severe. Indeed, Kussmaul originally indentified this type of breathing as a sign of coma and imminent death in diabetic patients.

Duration of fasting, presence or absence of hepatomegaly and Kussmaul breathing provide clues to the differential diagnosis of hypoglycemia in the inborn errors of metabolism.[4]

References

1. ^ Kussmaul breathing has reduced or normal frequency, not increased, see [1], [2], [3] etc. Note that this occurs only in advanced stages of acidosis, and is farely rarely reached. In less severe cased of acidosis, rapid, shallow breathing is seen. Kussmaul breathing is a kind of very deep, gasping, desperate breathing.
2. ^ Hyperventilation means breathing that is faster and/or deeper than normal. Kussmaul breathing is deep but not fast (i.e no tachypnea).
3. ^ A. Kussmaul: Zur Lehre vom Diabetes mellitus. Über eine eigenthümliche Todesart bei Diabetischen, über Acetonämie, Glycerin-Behandlung des Diabetes und Einspritzungen von Diastase in’s Blut bei dieser Krankheit., Deutsches Archiv für klinische Medicin, Leipzig, 1874, 14: 1-46. English translation in Ralph Hermon Major (1884-1970), Classic Descriptions of Disease. Springfield, C. C. Thomas, 1932. 2nd edition, 1939, 3rd edition, 1945.
4. ^ Current Diagnosis and Treatment in Pediatrics, 18th Edition, Page:989
Breathing transports oxygen into the body and carbon dioxide out of the body. Aerobic organisms require oxygen to create energy via respiration, in the form of energy-rich molecules such as glucose. The medical term for normal relaxed breathing is eupnoea.
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MeSH D000138
For acidosis referring to acidity of the urine, see renal tubular acidosis.
Acidosis is an increased acidity (i.e. an increased hydrogen ion concentration). If not further qualified, it refers to acidity of the blood plasma.
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Hyperventilation
Classifications and external resources

ICD-10 R 06.4
ICD-9 786.01

In medicine, hyperventilation (or overbreathing
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Adolph Kussmaul (February 22, 1822 - May 28, 1902) was a German physician and a leading clinician of his time. He was born as the son and grandson of physicians at Graben near Karlsruhe and studied at Heidelberg.
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The 19th Century (also written XIX century) lasted from 1801 through 1900 in the Gregorian calendar. It is often referred to as the "1800s.
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Germans (German: Deutsche) are defined as an ethnic group, in the sense of sharing a common German culture, citizenship, speaking the German language as a mother tongue and being born in Germany.
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physician applies to a person who practices some type of medicine. Such medical practitioners are concerned with maintaining or restoring human health through the study, diagnosis and treatment of disease and injury, through both an area of knowledge
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respiratory system generally includes tubes, such as the bronchi, used to carry air to the lungs, where gas exchange takes place. A diaphragm pulls air in and pushes it out. Respiratory systems of various types are found in a wide variety of organisms.
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Metabolic acidosis
Classification & external resources

Davenport diagram
ICD-10 E 87.2
ICD-9 276.2

DiseasesDB 92
MedlinePlus 000335
eMedicine emerg/312   med/1458 ped/15

In medicine, metabolic acidosis
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Diabetes mellitus
Classification & external resources

ICD-10 E 10. –E 14.
ICD-9 250

MedlinePlus 001214
eMedicine med/546   emerg/134

MeSH C18.452.394.
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Diabetic ketoacidosis (DKA) is a life-threatening complication in patients with untreated diabetes mellitus (chronic high blood sugar or hyperglycemia). Near complete deficiency of insulin and elevated levels of certain stress hormones combine to cause DKA.
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Carbon dioxide is a chemical compound composed of two oxygen atoms covalently bonded to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state.
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In animal physiology, respiration is the transport of oxygen from the ambient air to the tissue cells and the transport of carbon dioxide in the opposite direction. This is in contrast to the biochemical definition of respiration, which refers to cellular respiration
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Carbon dioxide is a chemical compound composed of two oxygen atoms covalently bonded to a single carbon atom. It is a gas at standard temperature and pressure and exists in Earth's atmosphere in this state.
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Air hunger is the sensation of the urge to breathe. It is usually caused by the detection of high levels of carbon dioxide in the blood by sensors in the carotid sinus and is one of the body's homeostatic mechanisms to ensure proper oxygenation.
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<noinclude> </noinclude> Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Liver plays central role in transformation and clearance of most chemicals and is susceptible to the toxicity from these agents.
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In medicine, differential diagnosis (sometimes abbreviated DDx or ΔΔ) is the systematic method physicians use to identify the disease causing a patient's symptoms.

Before a medical condition can be treated, it must be identified.
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MeSH D007003 Hypoglycemia (hypoglycaemia in British English) is a medical term referring to a pathologic state produced by a lower than normal level of glucose (sugar) in the blood. The term hypoglycemia literally means "under-sweet blood" (Gr.
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Hyperventilation
Classifications and external resources

ICD-10 R 06.4
ICD-9 786.01

In medicine, hyperventilation (or overbreathing
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