Information about Intersalt Study
The Intersalt study was a landmark observational study that showed a strong association between dietary salt and risk of cardiovascular disease.[1] The results were disputed by the Salt Institute (the salt producers' trade organisation), who demanded that the results be handed over for re-analysis.[2] A re-analysis was published in 1996 and the results were the same.[3] The results have since been confirmed by the TOHP I and TOHP II studies.[4]
References
1. ^ Intersalt Cooperative Research Group (1988). "Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion". Br Med J 297 (6644): 319–28. PMID 3416162.
2. ^ Godlee F (2007). "Editor's choice: Time to talk salt". Br Med J 334 (7599). DOI:10.1136/bmj.39196.679537.47.
3. ^ Elliott P, Stamler J, Nichols R, et al. (1996). "Intersalt revisited: further analyses of 24 hour sodium excretion and blood pressure within and across populations. Intersalt Cooperative Research Group". Br Med J 312 (7041): 1249–53. PMID 8634612.
4. ^ Cook NR, Cutler JA, Obarzanek E, et al. (2007). "Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP)". Br Med J 334: 885–8. DOI:10.1136/bmj.39147.604896.55.
2. ^ Godlee F (2007). "Editor's choice: Time to talk salt". Br Med J 334 (7599). DOI:10.1136/bmj.39196.679537.47.
3. ^ Elliott P, Stamler J, Nichols R, et al. (1996). "Intersalt revisited: further analyses of 24 hour sodium excretion and blood pressure within and across populations. Intersalt Cooperative Research Group". Br Med J 312 (7041): 1249–53. PMID 8634612.
4. ^ Cook NR, Cutler JA, Obarzanek E, et al. (2007). "Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP)". Br Med J 334: 885–8. DOI:10.1136/bmj.39147.604896.55.
MeSH D002318 Cardiovascular disease refers to the class of diseases that involve the heart or blood vessels (arteries and veins). While the term technically refers to any disease that affects the cardiovascular system, it is usually used to refer to those related to
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