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Information about Hydrochloride

In chemistry, hydrochlorides are salts resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (mostly amines). This is also known as muriate, derived from hydrochloric acid's other name: muriatic acid.

For example, reaction of pyridine (C5H5N) with hydrochloric acid (HCl) yields pyridine hydrochloride (C5H5N·HCl). Even though this style of formulas is often used for denoting the hydrochlorides, the dot incorrectly implies that the two molecules are weakly bonded together. It is the salt C5H5NH+ Cl- with correct chemical name pyridinium chloride.

Uses

Converting insoluble amines into hydrochlorides is a common way to make them water- and acid-soluble. This is particularly desirable for substances used in medications. Many pharmaceutical substances are prepared as hydrochlorides so that they may be quickly absorbed in the gastrointestinal tract; the body usually absorbs a hydrochloride within 15 - 30 minutes.

Examples of hydrochlorides in medical uses are many, ranging from over-the-counter sinus relief to antidepressants.
This article is about the term salt as referred to in chemistry. For the everyday meaning, see salt or its main ingredient, sodium chloride. For other meanings of the word salt, see salt (disambiguation).

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hydrochloric acid is the aqueous (water-based) solution of hydrogen chloride gas (HCl). It is a strong acid, the major component of gastric acid and of wide industrial use. Hydrochloric acid must be handled with appropriate safety precautions because it is a highly corrosive liquid.
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    In chemistry, a base is most commonly thought of as a substance that can accept protons. This refers to the Brønsted-Lowry theory of acids and bases. Alternate definitions of bases include electron pair donors (Lewis), and as sources of hydroxide anions (Arrhenius).
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    Amines are organic compounds and a type of functional group that contain nitrogen as the key atom. Structurally amines resemble ammonia, wherein one or more hydrogen atoms are replaced by organic substituents such as alkyl and aryl groups.
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    Pyridine is a chemical compound with the formula C5H5N. It is a liquid with a distinctively putrid, fishy odour. Pyridine is a simple and fundamentally important heterocyclic aromatic organic compound that is structurally related to benzene, wherein one CH
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    Solubility is a physical property referring to the ability for a given substance, the solute, to dissolve in a solvent.[1] It is measured in terms of the maximum amount of solute dissolved in a solvent at equilibrium. The resulting solution is called a saturated solution.
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    A pharmaceutical company, or drug company, is a commercial business whose focus is to research, develop, market and/or distribute drugs, most commonly in the context of healthcare. They can deal in generic and/or brand medications.
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    antidepressant, is a psychiatric medication or other substance (nutrient or herb) used for alleviating depression or dysthymia ('milder' depression). Drug groups known as MAOIs, tricyclics and SSRIs are particularly associated with the term.
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