Information about Holocrine

Holocrine is a classification of exocrine glands in the study of Histology.

Holocrine secretions are produced within the cell followed by the rupture of the plasma membrane, thus releasing the cellular contents into the lumen.

Examples of holocrine glands include the sebaceous glands of the skin and the meibomian glands of the eyelid.

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Exocrine glands are glands that secrete their products (enzymes) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands).
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Histology (from the Greek ἱστός) is the study of tissue sectioned as a thin slice, using a microtome. It can be described as microscopic anatomy.
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Lumen can mean:
  • Lumen (unit), the SI unit of luminous flux
  • Lumen (anatomy), the cavity or channel within a tubular structure
  • Thylakoid lumen, the inner membrane space of the chloroplast

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The sebaceous glands are glands found in the skin of mammals.

Locations and morphology

A branched type of acinar gland, these glands exist in humans throughout the skin except in the palms of the hands and soles of the feet.
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The meibomian glands (or tarsal glands) are a special kind of sebaceous glands at the rim of the eyelids, responsible for the supply of sebum, an oily substance that prevents evaporation of the eye's tear film, prevents tear spillage onto the cheek, and makes the closed
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An eyelid is a thin fold of skin and muscle that covers and protects an eye. With the exception of the prepuce and the labia minora, it has the thinnest skin of the whole body. The levator palpebrae superioris muscle retracts the eyelid to "open" the eye.
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gland is an organ in an animal's body that synthesizes a substance for release such as hormones, often into the bloodstream (endocrine gland) or into cavities inside the body or its outer surface (exocrine gland).
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Endocrine glands are glands that secrete their product directly into the blood rather than through a duct. This group contains the glands of the Endocrine system.

External links

  • Endocrine+glands at eMedicine Dictionary

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Exocrine glands are glands that secrete their products (enzymes) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands).
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Merocrine (eccrine) is a classification of exocrine glands in the study of Histology.

A cell is classified as merocrine if the secretions of that cell dump directly into the lumen.
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Apocrine is a term used to classify exocrine glands in the study of histology. Cells which are classified as apocrine bud their secretions off through the plasma membrane producing membrane bound vesicles in the lumen.
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If a gland retains its shape as a tube throughout it is termed a tubular gland.[1] [2]

Tubular glands are further classified as one of the following:

Name Description Location
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alveolar glands[1] (or saccular glands[2][3], or acinar glands[4], or acinous glands[5][6]).
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Serous glands contain serous acini, a grouping of serous cells that secrete a fluid, isotonic with blood plasma, that contains enzymes such as alpha amylase.

Serous glands are most common in the parotid gland, but are also present in the submandibular gland and, to a far
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Mucous glands, found in several different parts of the body, typically stain lighter than serous glands during standard histological preparation. Most are multicellular, but goblet cell are single-celled glands.
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A serous demilune is a cap in the shape of a half-moon (hence the name, "demilune") on some salivary glands.

The serous demilune is an artifact from traditional methods of preparing samples. Samples are traditionally preserved and fixed in formaldehyde.
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In anatomy and physiology, a duct is a circumscribed channel leading from an exocrine gland or organ.

Types of ducts

Examples include:

Duct From To Carries
Lactiferous duct mammary gland nipple milk
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A interlobar duct is a gland duct which connects more than one anatomic lobe.

Examples of where it can be found include the parotid gland[1] and submandibular gland.
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A Interlobular duct is a gland duct which connects more than one lobule. It is smaller than an interlobar duct.

Examples of where it can be found include
  • pancreas[1][2]
  • mammary gland[3]
  • parotid gland[4][5]

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An intralobular duct is the portion of an exocrine gland inside a lobule, leading directly from intercalated duct to an interlobular duct.

They can be seen in:
  • pancreas[1][2][3][4]
  • salivary glands[5]

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A striated duct is a gland duct which connects an intercalated duct to an interlobular duct. It is characterized by its folded membrane.[1] [2]

Their epithelium can be simple cuboidal or simple columnar.
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The intercalated duct is the portion of an exocrine gland leading directly from the acinus, and to a striated duct.

They are part of the intralobular duct.

They have the thinnest epithelium of any part of the duct system, and the epithelium is usually classified as
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An acinus (adjective: acinar, plural acini) refers to the berry-shaped termination of an exocrine gland, where the secretion is produced.

They are found in many organs, including:
  • the stomach[1]
  • the sebaceous gland of the scalp

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