Information about Gastric Chief Cell
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| H&E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation | |
| A fundus gland. A. Transverse section of gland. | |
| Dorlands/Elsevier | c_18/12222877 |
It works in conjunction with the parietal cell which releases gastric acid, converting the pepsinogen into pepsin.
Nomenclature
The terms "chief cell" and "zymogenic cell" are often used without the word "gastric" to name this type of cell. However those terms can also be used to describe other cell types (for example, parathyroid chief cells.))
human chief cells
See also
External links
- Anatomy Atlases - Microscopic Anatomy, plate 01.05
- Histology at BU 22201loa - "Ultrastructure of the Cell: chief cells and enteroendocrine cell"
- Histology at BU 11304loa - "Digestive System: Alimentary Canal: fundic stomach, gastric glands, base"
- c_18/12224535 at Dorland's Medical Dictionary
- Physiology at MCG 6/6ch4/s6ch4_8
Digestive system, physiology: gastrointestinal physiology | |
|---|---|
| Enteric nervous system | Meissner's plexus - Auerbach's plexus |
| Exocrine | Chief cells (Pepsinogen) - Parietal cells (Gastric acid, Intrinsic factor) - Goblet cells (Mucus) |
| Endocrine/paracrine | G cells (gastrin), D cells (somatostatin) - ECL cells (Histamine) - enterogastrone: I cells (CCK), K cells (GIP), S cells (secretin) |
| Border | Brunner's glands - Paneth cells - Enterocytes |
| Fluids | Saliva - Bile - Intestinal juice - Gastric juice - Pancreatic juice |
| Processes | Swallowing - Vomiting - Peristalsis (Interstitial cell of Cajal) - Migrating motor complex - Borborygmus - Gastrocolic reflex - Segmentation contractions - Defecation |
Elsevier, the world's largest publisher of medical and scientific literature, forms part of the Reed Elsevier group. Based in Amsterdam, the company has substantial operations in the UK, USA and elsewhere.
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In anatomy, the stomach is a bean-shaped hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication. The word stomach is derived from the Latin stomachus, which derives from the Greek word
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Pepsin is a digestive protease (EC 3.4.23.1 ) released by the chief cells in the stomach that functions to degrade food proteins into peptides.
According to American Heritage Dictionary, pepsin derives from the Greek word pepsis, meaning digestion (
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According to American Heritage Dictionary, pepsin derives from the Greek word pepsis, meaning digestion (
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Identifiers
Symbol CYMP
Entrez 1542
HUGO 2588
OMIM 118943
Other data
EC number 3.4.23.4
Locus Chr. 1
Chymosin (or rennin) is an aspartic acid protease enzyme found in rennet.
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Symbol CYMP
Entrez 1542
HUGO 2588
OMIM 118943
Other data
EC number 3.4.23.4
Locus Chr. 1
Chymosin (or rennin) is an aspartic acid protease enzyme found in rennet.
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Parietal cells (also called oxyntic cells) are the stomach epithelium cells which secrete gastric acid and intrinsic factor.
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Acid production
Parietal cells produce gastric acid (hydrochloric acid) in response to histamine (via H2..... Click the link for more information.
Gastric acid is one of the main secretions of the stomach, together with several enzymes and intrinsic factor. Chemically it is an acid solution consisting mainly of hydrochloric acid (HCl), and small quantities of potassium chloride (KCl) and sodium chloride (NaCl).
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Pepsin is a digestive protease (EC 3.4.23.1 ) released by the chief cells in the stomach that functions to degrade food proteins into peptides.
According to American Heritage Dictionary, pepsin derives from the Greek word pepsis, meaning digestion (
..... Click the link for more information.
According to American Heritage Dictionary, pepsin derives from the Greek word pepsis, meaning digestion (
..... Click the link for more information.
A zymogen (or proenzyme) is an inactive enzyme precursor. A zymogen requires a biochemical change (such as a hydrolysis reaction revealing the active site, or changing the configuration to reveal the active site) for it to become an active enzyme.
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Parathyroid chief cells are cells in the parathyroid glands which produce parathyroid hormone.
The end result of increased secretion by the chief cells of a parathyroid gland is an increase in the serum level of Calcium.
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The end result of increased secretion by the chief cells of a parathyroid gland is an increase in the serum level of Calcium.
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Gastric acid is one of the main secretions of the stomach, together with several enzymes and intrinsic factor. Chemically it is an acid solution consisting mainly of hydrochloric acid (HCl), and small quantities of potassium chloride (KCl) and sodium chloride (NaCl).
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The fundus glands (or fundic glands, or gastric glands) are found in the body and fundus of the stomach.
They are simple tubes, two or more of which open into a single duct.
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They are simple tubes, two or more of which open into a single duct.
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Boston University (BU) is a private research university located in Boston, Massachusetts, United States. Although chartered by the Massachusetts Legislature in 1869, Boston University traces its roots to the establishment of the Newbury Biblical Institute in Newbury,
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Boston University (BU) is a private research university located in Boston, Massachusetts, United States. Although chartered by the Massachusetts Legislature in 1869, Boston University traces its roots to the establishment of the Newbury Biblical Institute in Newbury,
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Dorland's is the brand name of several different medical dictionaries and ancillary products, chiefly Dorland's Illustrated Medical Dictionary (currently in its 31st edition) and Dorland's Pocket Medical Dictionary (currently in its 27th edition).
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Medical College of Georgia is the smallest of four research schools in the University System of Georgia (USG). MCG currently has 5 undergraduate and graduate schools on campus: The School of Medicine, School of Dentistry, School of Nursing, School of Allied Health, and Graduate
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The digestive system is the organ system that breaks down and absorbs nutrients that are essential for growth and maintenance. The digestive system includes the mouth, esophagus, stomach, pancreas, liver, gallbladder, duodenum, jejunum, ileum, (intestines), rectum, and anus.
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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems.
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Gastrointestinal physiology is a branch of human physiology addressing the physical function of the gastrointestinal system.
Hormone Source Description
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peristalsis
- muscularis mucosae
- muscularis externa
gastric hormones
Hormone Source Description
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enteric nervous system (ENS) is the part of the nervous system that directly controls the gastrointestinal system. It is capable of autonomous functions such as the coordination of reflexes, although it receives considerable innervation from the autonomic nervous system and
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plexus of the submucosa (Meissner's plexus, Submucous plexus, submucosal plexus) is derived, and is formed by branches which have perforated the circular muscular fibers.
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Part of the enteric nervous system, Auerbach's plexus (or myenteric plexus) exists between the longitudinal and circular layers of muscularis externa in the gastrointestinal tract and provides motor innervation to both layers and secretomotor innervation to the mucosa.
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Pepsin is a digestive protease (EC 3.4.23.1 ) released by the chief cells in the stomach that functions to degrade food proteins into peptides.
According to American Heritage Dictionary, pepsin derives from the Greek word pepsis, meaning digestion (
..... Click the link for more information.
According to American Heritage Dictionary, pepsin derives from the Greek word pepsis, meaning digestion (
..... Click the link for more information.
Parietal cells (also called oxyntic cells) are the stomach epithelium cells which secrete gastric acid and intrinsic factor.
..... Click the link for more information.
Acid production
Parietal cells produce gastric acid (hydrochloric acid) in response to histamine (via H2..... Click the link for more information.
Gastric acid is one of the main secretions of the stomach, together with several enzymes and intrinsic factor. Chemically it is an acid solution consisting mainly of hydrochloric acid (HCl), and small quantities of potassium chloride (KCl) and sodium chloride (NaCl).
..... Click the link for more information.
..... Click the link for more information.
Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B 12 later on in the terminal ileum.
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Goblet cells are glandular simple columnar epithelial cells whose sole function is to secrete mucus.
The majority of the cell's cytoplasm is occupied by mucinogen granules, except at the bottom.
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The majority of the cell's cytoplasm is occupied by mucinogen granules, except at the bottom.
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highly specialized aspect of its associated subject.
Please help [ improve this article] by adding more general information.
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Mucus is a slippery secretion of the lining of the mucous membranes in the body.
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In anatomy, the G cell is a type of cell in the stomach that secretes gastrin.[1] It works in conjunction with gastric chief cells and parietal cells.
G cells are found deep with the gastric glands of the stomach antrum, and occasionally in the pancreas.
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G cells are found deep with the gastric glands of the stomach antrum, and occasionally in the pancreas.
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In humans, gastrin is a hormone that stimulates secretion of gastric acid by the parietal cells of the stomach. It is released by G cells in the stomach and duodenum.
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Physiology
Genetics
The GAS..... Click the link for more information.
Delta cells (δ-cells or D cells) are somatostatin producing cells.
They can be found in the stomach, intestine and the Islets of Langerhans in the pancreas.
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They can be found in the stomach, intestine and the Islets of Langerhans in the pancreas.
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