Information about Extraglomerular Mesangial Cells
Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the thick ascending limb of Henle and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood. Although is it has been associated with the secretion of EPO. [1]
The renin-angiotensin system (RAS) or the renin-angiotensin-aldosterone system (RAAS) is a hormone system that helps regulate long-term blood pressure and extracellular volume in the body.
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Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the thick ascending limb of Henle and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood. Although is it has been associated with the secretion of EPO. [1]
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The kidneys are organs that filter wastes (such as urea) from the blood and excrete them, along with water, as urine. The medical field that studies the kidneys and diseases of the kidney is called nephrology[1].
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glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. It receives its blood supply from an afferent arteriole of the renal circulation.
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The vascular pole is a location of the glomerulus. At the vascular pole, the afferent arterioles and efferent arterioles enter the Bowman's capsule.
The urinary pole is at the other end.
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The urinary pole is at the other end.
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In the kidney, the macula densa is an area of closely packed specialized cells lining the region of the distal convoluted tubule (DCT) lying next to the glomerular vascular pole.
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juxtaglomerular apparatus is a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning distal
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In the kidney, the macula densa is an area of closely packed specialized cells lining the region of the distal convoluted tubule (DCT) lying next to the glomerular vascular pole.
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The thick ascending limb of loop of Henle (or distal straight tubule) can be divided into two parts: that in the renal medulla, and that in the renal cortex.
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Medullary thick ascending limb
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In the kidney, the juxtaglomerular cells (JG cells, also known as granular cells) are cells that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells in the wall of the afferent arteriole that delivers blood to the glomerulus.
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The afferent arterioles are a group of blood vessels that supply the nephrons in many excretory systems.
The afferent arterioles branch from the renal artery which supplies blood to the kidneys.
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The afferent arterioles branch from the renal artery which supplies blood to the kidneys.
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Blood pressure (strictly speaking: vascular pressure) refers to the force exerted by circulating blood on the walls of blood vessels, and constitutes one of the principal vital signs.
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For an autonomous region of Nicaragua, see .
The renin-angiotensin system (RAS) or the renin-angiotensin-aldosterone system (RAAS) is a hormone system that helps regulate long-term blood pressure and extracellular volume in the body.
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The mesangium is an inner layer of the glomerulus, within the basement membrane surrounding the glomerular capillaries. This term is often used interchangeably with mesangial cell, but in this context refers specifically to the intraglomerular mesangial cells.
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Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle.
There are three primary functions of intraglomerular mesangial cells: filtration, structural support, and phagocytosis.
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There are three primary functions of intraglomerular mesangial cells: filtration, structural support, and phagocytosis.
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The College of Medicine at Urbana-Champaign is a graduate school at the University of Illinois at Urbana-Champaign.The UIC College of Medicine at Urbana-Champaign is located at the original campus of the University (with 42,000 students, undergraduate and graduate) and offers a
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Dorland's is the brand name of several different medical dictionaries and ancillary products, chiefly Dorland's Illustrated Medical Dictionary (currently in its 31st edition) and Dorland's Pocket Medical Dictionary (currently in its 27th edition).
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The urinary system is the organ system that produces, stores, and eliminates urine. In humans it includes two kidneys, two ureters, the bladder, and the urethra. The analogous organ in invertebrates is the nephridium.
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The kidneys are organs that filter wastes (such as urea) from the blood and excrete them, along with water, as urine. The medical field that studies the kidneys and diseases of the kidney is called nephrology[1].
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renal fascia (also known as Gerota's fascia after the Romanian anatomist Dimitrie Gerota).
At the lateral border of the kidney the renal fascia splits into an anterior and a posterior layer.
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At the lateral border of the kidney the renal fascia splits into an anterior and a posterior layer.
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The renal capsule is a tough fibrous layer surrounding the kidney and covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
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The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. In the adult, it forms a continuous smooth outer zone with a number of projections (cortical columns) that extend down between the pyramids.
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The renal column (or Bertin column, or column of Bertin) is a medullary extension of the renal cortex in between the renal pyramids. It allows the cortex to be better anchored.
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The renal medulla is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the arcuate arterioles.
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The renal sinus is a cavity within the kidney which is occupied by the renal pelvis, renal calyces, blood vessels, nerves and fat.
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External links
- Renal+sinus at eMedicine Dictionary
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Renal pyramids (or malpighian pyramids) are cone-shaped tissues of the kidney. The renal medulla is made up of 8 to 18 of these conical subdivisions. The broad base of each pyramid faces the renal cortex, and its apex, or papilla, points internally.
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The renal lobe is a portion of a kidney consisting of a renal pyramid and the renal cortex above it. [1]
It is visible without a microscope, though it is easier to see in humans than in animals.
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It is visible without a microscope, though it is easier to see in humans than in animals.
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A cortical lobule (or renal lobule) is a part of a renal lobe. It consists of the nephrons grouped around a single medullary ray, and draining into a single collecting duct.
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The medullary ray is the middle part of the cortical lobule or renal lobule, consisting of a group of straight tubes to the collecting ducts.
Their name is potentially misleading -- the "medullary" refers to their destination, not their location.
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Their name is potentially misleading -- the "medullary" refers to their destination, not their location.
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A nephron (from Greek νεφρός (nephros) meaning "kidney") is the basic structural and functional unit of the kidney. Its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood,
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renal circulation receives around 20% of the cardiac output. It branches from the abdominal aorta and returns blood to the ascending vena cava. It is the blood supply to the kidney, and contains many specialized blood vessels.
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The renal arteries normally arise off the side of the abdominal aorta, immediately below the superior mesenteric artery, and supply the kidneys with blood. Each is directed across the crus of the diaphragm, so as to form nearly a right angle with the aorta.
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