Information about Cdb 4124
| CDB-4124 | |
|---|---|
| IUPAC name | 17α-acetoxy-21-methoxy-11β-[4-N,N-dimethylaminophenyl]-19-norpregna-4,9-diene-3,20-dione) |
| Identifiers | |
| CAS number | |
| MeSH | |
| Properties | |
| Molecular formula | C31H39NO5 |
| Molar mass | 505.65 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 C, 100 kPa) | |
References
1. ^ Attardi BJ, Burgenson J, Hild SA, Reel JR (2004). "In vitro antiprogestational/antiglucocorticoid activity and progestin and glucocorticoid receptor binding of the putative metabolites and synthetic derivatives of CDB-2914, CDB-4124, and mifepristone". J Steroid Biochem Mol Biol 88 (3): 277-88. DOI:10.1016/j.jsbmb.2003.12.004. PMID 15120421.
IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. It is developed and kept up to date under the auspices of the International Union of Pure and Applied Chemistry (IUPAC).
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CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. They are also referred to as CAS numbers, CAS RNs or CAS #s.
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Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed
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A chemical formula is a concise way of expressing information about the atoms that constitute a particular chemical compound. A chemical formula is also a short way of showing how a chemical reaction occurs.
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Molar mass, symbol M,[1] is the mass of one mole of a substance (chemical element or chemical compound).[2] It is a physical property which is characteristic of each pure substance.
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standard state of a material is its state at 1 bar (100 kilopascals exactly). This pressure was changed from 1 atm (101.325 kilopascals) by IUPAC in 1990.[1] The standard state of a material can be defined at any given temperature, most commonly 25 degrees Celsius,
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A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor. A characteristic that distinguishes such substances from receptor full agonists (such as progesterone) and full antagonists (such as RU 486) is that their action differs in
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digital object identifier (or DOI) is a permanent identifier given to a document, which is not related to its current location. A typical use of a DOI is to give a scientific paper or article a unique identifying number that can be used by anyone to locate details of the paper, and
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Sex steroids, also known as gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. The term sex hormone nearly always is synonymous with sex steroid.
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A section of the Anatomical Therapeutic Chemical Classification System.
G Genito-urinary system and sex hormones
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G Genito-urinary system and sex hormones
G03A Hormonal contraceptives for systemic use
G03AA Progestogens and estrogens, fixed combinations
- G03AA01 Etynodiol and estrogen
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A section of the Anatomical Therapeutic Chemical Classification System.
L Antineoplastic and immunomodulating agents
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L Antineoplastic and immunomodulating agents
L02A Hormones and related agents
L02AA Estrogens
- L02AA01 Diethylstilbestrol
- L02AA02 Polyestradiol phosphate
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Progestagens (also spelled progestogens or gestagens) are hormones that produce effects similar to those of progesterone, the only natural progestagen. All other progestogens are synthetic and are often referred to as progestins.
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The progesterone receptor is an intracellular steroid receptor that specifically binds progesterone. Expressed by a single gene (chromosome 11q22), it has two main forms, A and B, that differ in their molecular weight.
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Progesterone is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation) and embryogenesis of humans and other species. Progesterone belongs to a class of hormones called progestogens, and is the major naturally occurring human
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Desogestrel is a molecule used in hormonal contraceptives.
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Controversy
In February of 2007, the consumer adovcacy group Public Citizen released a petition requesting that the FDA ban oral contraceptives containing desogestrel, citing studies going as far back as 1995 that..... Click the link for more information.
Drospirenone is a synthetic progestin that is an analog to spironolactone. Its molecular weight is 366.5 and its molecular formula is C24H30O3.
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Properties and uses
The compound is part of certain birth control formulations...... Click the link for more information.
Dydrogesterone is a progestogen hormone. The brand name is Duphaston and manufactured by Solvay Pharmaceuticals.
Dydrogesterone was first introduced to the market in 1961, and is currently approved in over 100 countries world-wide.
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Dydrogesterone was first introduced to the market in 1961, and is currently approved in over 100 countries world-wide.
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Ethisterone is a progestogen hormone.
The first orally active progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone), the 17α-ethynyl analog of testosterone, was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur
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The first orally active progestin, ethisterone (pregneninolone, 17α-ethynyltestosterone), the 17α-ethynyl analog of testosterone, was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur
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Etonogestrel is a molecule used in hormonal contraceptives, most notably the subdermal implant Implanon.
Etonogestrel, the specific progestin used in NuvaRing, is the active metabolite of the inactive prodrug desogestrel, one of two third-generation progestins found in some
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Etonogestrel, the specific progestin used in NuvaRing, is the active metabolite of the inactive prodrug desogestrel, one of two third-generation progestins found in some
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Ethynodiol diacetate is a molecule used in hormonal contraceptives.
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Gestodene is a progestogen used in hormonal contraceptives.
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See also
- Progestin
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Gestonorone is a progestagen hormone.
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Levonorgestrel (or -norgestrel or -norgestrel) is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.
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Chemistry
Chemically, it is a hormonally active levorotatory enantiomer of the racemic mixture norgestrel...... Click the link for more information.
Lynestrenol is a progestagen hormone.
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Medroxyprogesterone is a progestin, and is commonly a component of hormonal contraceptives. It can be used in the treatment of endometriosis, abnormal menstrual bleeding or amenorrhea.
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Megestrol is a progesterone derivative with antineoplastic properties used in the treatment of advanced carcinoma of the breast and endometrium. When given in relatively high doses, Megestrol can substantially increase appetite in most individuals, even those with advanced cancer.
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Norelgestromin is a molecule used in hormonal contraceptives. This form of progestin is used in the contraceptive patch, Ortho Evera.
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See also
- Progestin
- Contraceptive patch
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Norethisterone (or norethindrone) (or 19-nor-17α-ethynyltestosterone) is a molecule used in some combined oral contraceptive pills and in some progestogen only pills.
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Norethynodrel was the progestin used in Enovid, the first oral contraceptive.
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Norgestimate is a molecule used in hormonal contraceptives.
Norgestimate is a form of progesterone, which is a female hormone important for the regulation of ovulation and menstruation.
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Norgestimate is a form of progesterone, which is a female hormone important for the regulation of ovulation and menstruation.
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