Information about Bengt I. Samuelsson
Bengt Ingemar Samuelsson (born May 21, 1934) is a Swedish biochemist.
He was born in Halmstad in southwest Sweden and studied at Stockholm University, where he became a professor in 1967. He shared with Sune K. Bergström and John R. Vane the 1982 Nobel Prize for Physiology or Medicine for discoveries concerning prostaglandins and related substances. In 1975,he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Sune K. Bergström . Discussing the role of prostaglandins in the body, Samuelsson explained, "It's a control system for the cells that participates in many biological functions. There are endless possibilities of manipulating this system in drug development."
His research interests were originally in cholesterol metabolism with importance to reaction mechanisms. Following the structural work on prostaglandins along with Sune Bergström he has interested mainly in transformation products of arachidonic acid. This has directed to the identification of endoperoxides, thromboxanes and the leukotrienes, and his group has chiefly been involved in studying the chemistry, biochemistry and biology of these compounds and their function in biological control system. The research has implications in numerous clinical areas, especially in thrombosis, inflammation, and allergy.
This field grew enormously since those days. Between 1981 and 1995 about three thousand papers per year were published that openly used the expression "prostaglandins," or related terms such as "prostacyclins," "leukotrienes," and "thromboxanes," in their labels and titles.
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ICD-10 T 78.4
ICD-9 995.
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He was born in Halmstad in southwest Sweden and studied at Stockholm University, where he became a professor in 1967. He shared with Sune K. Bergström and John R. Vane the 1982 Nobel Prize for Physiology or Medicine for discoveries concerning prostaglandins and related substances. In 1975,he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Sune K. Bergström . Discussing the role of prostaglandins in the body, Samuelsson explained, "It's a control system for the cells that participates in many biological functions. There are endless possibilities of manipulating this system in drug development."
His research interests were originally in cholesterol metabolism with importance to reaction mechanisms. Following the structural work on prostaglandins along with Sune Bergström he has interested mainly in transformation products of arachidonic acid. This has directed to the identification of endoperoxides, thromboxanes and the leukotrienes, and his group has chiefly been involved in studying the chemistry, biochemistry and biology of these compounds and their function in biological control system. The research has implications in numerous clinical areas, especially in thrombosis, inflammation, and allergy.
This field grew enormously since those days. Between 1981 and 1995 about three thousand papers per year were published that openly used the expression "prostaglandins," or related terms such as "prostacyclins," "leukotrienes," and "thromboxanes," in their labels and titles.
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Halmstad ['hulm-stɑː(d)] is a port, university, industrial and recreational city at the mouth of the Nissan River in Halland County, south-western Sweden. The river empties into the Kattegatt.
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(Royal) "För Sverige - I tiden" 1
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Stockholm University (Stockholms universitet) is a state university in Stockholm, Sweden. It has about 37,000 students studying at four faculties.
In 1878, the university college Stockholm högskola
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Sune Karl Bergström (born January 10, 1916 in Stockholm, Sweden; died August 15, 2004) was a Swedish biochemist. In 1975, he was appointed to the Nobel Foundation Board of Directors in Sweden.
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Sir John Robert Vane (March 29, 1927 – November 19, 2004) was a British pharmacologist. His father was the son of Jewish immigrants from Russia and his mother came from a Worcestershire farming family.
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prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring.
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Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers that have made an outstanding contribution in basic research in the fields of biology or biochemistry.
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Columbia University is a private university in the United States and a member of the Ivy League. Its main campus lies in the Morningside Heights neighborhood of the borough of Manhattan, in New York City.
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Sune Karl Bergström (born January 10, 1916 in Stockholm, Sweden; died August 15, 2004) was a Swedish biochemist. In 1975, he was appointed to the Nobel Foundation Board of Directors in Sweden.
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prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring.
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Cholesterol is a sterol (a combination steroid and alcohol), a lipid found in the cell membranes of all tissues, and is transported in the blood plasma of all animals. Because cholesterol is synthesized by all eukaryotes, trace amounts of cholesterol are also found in membranes of
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Prostaglandin H2 is a type of Prostaglandin which is derived from arachidonic acid and is a precursor for many other biologically significant molecules:
It is acted upon by:
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It is acted upon by:
- prostacyclin synthase to create prostacyclin
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Thromboxane is a member of the family of lipids known as eicosanoids. The two major thromboxanes are thromboxane A2 and thromboxane B2.
Thromboxane is named for its role in clot formation (thrombosis).
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Thromboxane is named for its role in clot formation (thrombosis).
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Leukotrienes are naturally produced eicosanoid lipid mediators, which may be responsible for a number of the effects of asthma and allergies. Leukotrienes use both autocrine signalling and paracrine signalling to regulate the body's response.
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Biochemistry is the study of the chemical processes in living organisms.[1] The word "biochemistry" comes from the Greek word βιοχημεία biochēmeia, which means "the chemistry of life.
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Biology (from Greek: βίος, bio, "life"; and λόγος, logos, "knowledge"), also referred to as the biological sciences, is the scientific study of life.
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MeSH D013927 Thrombosis is the formation of a clot or thrombus inside a blood vessel, obstructing the flow of blood through the circulatory system. Thromboembolism is a general term describing both thrombosis and its main complication which is embolisation.
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Inflammation (Latin, inflammatio, to set on fire) is the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.
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';
George Richards Minot, ';
William Parry Murphy, "for their discoveries concerning liver therapy in cases of anaemia"[31]
1935 Hans Spemann, '' German Empire "for his discovery of the organizer effect in embryonic development"[32]
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George Richards Minot, ';
William Parry Murphy, "for their discoveries concerning liver therapy in cases of anaemia"[31]
1935 Hans Spemann, '' German Empire "for his discovery of the organizer effect in embryonic development"[32]
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